Host-guest supramolecular chemistry in solid-state nanopores: potassium-driven modulation of ionic transport in nanofluidic diodes

被引：77

作者：

Perez-Mitta, Gonzalo ^{[1
]}

Albesa, Alberto G. ^{[1
]}

Knoll, Wolfgang ^{[2
]}

Trautmann, Christina ^{[3
]}

Toimil-Molares, Maria Eugenia ^{[3
]}

Azzaroni, Omar ^{[1
]}

机构：

[1] Univ Nacl La Plata, CONICET, Inst Invest Fisicoquim Teor & Aplicadas INIFTA, RA-1900 La Plata, Argentina

[2] Austrian Inst Technol, Vienna, Austria

[3] GSI Helmholtzzentrum Schwerionenforsch, Darmstadt, Germany

来源：

NANOSCALE | 2015年 / 7卷 / 38期

关键词：

TRACK-ETCHED MEMBRANES; CURRENT RECTIFICATION; PORES; NANOCHANNEL; CHANNELS; CURRENTS; SIGNAL; DNA;

D O I：

10.1039/c5nr04645a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We describe the use of asymmetric nanopores decorated with crown ethers for constructing robust signal-responsive chemical devices. The modification of single conical nanopores with 18-crown-6 units led to a nanodevice whose electronic readout, derived from the transmembrane ion current, can be finely tuned over a wide range of K+ concentrations. The electrostatic characteristics of the nanopore environment arising from host-guest ion-recognition processes taking place on the pore walls are responsible for tuning the transmembrane ionic transport and the rectification properties of the pore. This work illustrates the potential and versatility of host-guest chemistry, in combination with nanofluidic elements, as a key enabler to achieve addressable chemical nanodevices mimicking the ion transport properties and gating functions of specific biological channels.

引用

页码：15594 / 15598

页数：5

共 36 条

[1] Biosensing and Supramolecular Bioconjugation in Single Conical Polymer Nanochannels. Facile Incorporation of Biorecognition Elements into Nanoconfined Geometries [J].