PVA-based hydrogels for tissue engineering: A review

被引：391

作者：

Kumar, Anuj ^{[1
,2
]}

Han, Sung Soo ^{[1
,2
]}

机构：

[1] Yeungnam Univ, Sch Chem Engn, 280 Daehak Ro, Gyongsan 712749, South Korea

[2] Yeungnam Univ, Dept Nano Med & Polymer Mat, Gyongsan, South Korea

来源：

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS | 2017年 / 66卷 / 04期

关键词：

Cells; crosslinking; hydrogels; tissue engineering; scaffolds; PVA; POLYVINYL-ALCOHOL HYDROGEL; MOLECULAR-WEIGHT POLYETHYLENE; IN-SITU SYNTHESIS; POLY(VINYL ALCOHOL); MECHANICAL-PROPERTIES; CROSS-LINKING; PVA/PVP HYDROGELS; PHYSICOCHEMICAL PROPERTIES; BIODEGRADABLE HYDROGELS; CELLULOSE NANOCRYSTALS;

D O I：

10.1080/00914037.2016.1190930

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Poly (vinyl alcohol) (PVA) is a hydrophilic polymer with excellent biocompatibility and has been applied in various biomedical areas due to its favorable properties. PVA-based hydrogels have been recognized as promising biomaterials and suitable candidates for tissue engineering applications and can be manipulated to act various critical roles. However, due to some disadvantages (i.e., lack of cell-adhesive property), they needs further modification for desired and targeted applications. This review highlights recent progress in the design and fabrication of PVA-based hydrogels, including crosslinking and processing techniques. Finally, major challenges and future perspectives in tissue engineering are briefly discussed. [GRAPHICS] .

引用

页码：159 / 182

页数：24

共 252 条

[1] PVA/CM-chitosan/honey hydrogels prepared by using the combined technique of irradiation followed by freeze-thawing [J].