A SERS active bimetallic core-satellite nanostructure for the ultrasensitive detection of Mucin-1

被引：100

作者：

Feng, Jingjing ^{[1
]}

Wu, Xiaoling ^{[1
]}

Ma, Wei ^{[1
]}

Kuang, Hua ^{[1
]}

Xu, Liguang ^{[1
]}

Xu, Chuanlai ^{[1
]}

机构：

[1] Jiangnan Univ, Sch Food Sci & Technol, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 79期

基金：

中国国家自然科学基金;

关键词：

ENHANCED RAMAN-SCATTERING; BREAST-CANCER; NANOPARTICLE DIMERS; EARLY-DIAGNOSIS; NANOROD DIMERS; ION DETECTION; TUMOR-MARKER; SPECTROSCOPY; ASSEMBLIES; CHIRALITY;

D O I：

10.1039/c5cc05255f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this study, we established gold nanorods (Au NRs) core-silver nanoparticles (Ag NPs) satellite assemblies as an ultrasensitive aptamer-based SERS sensor for the detection of Mucin-1, a specific breast cancer marker protein. The limit of detection (LOD) was 4.3 aM and the wide linear range was 0.005-1 fM.

引用

收藏

页码：14761 / 14763

页数：3

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