The malnourished baby and infant

被引:115
作者
Barker, DJP [1 ]
机构
[1] Southampton Gen Hosp, MRC, Environm Epidemiol Unit, Southampton SO16 6YD, Hants, England
关键词
D O I
10.1093/bmb/60.1.69
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The growth of a baby is constrained by the nutrients and oxygen it receives from the mother. A mother's ability to nourish her baby is established during her own fetal life and by her nutritional experiences in childhood and adolescence, which determine her body size, composition and metabolism. Mother's diet in pregnancy has little effect on the baby's size at birth, but nevertheless programmes the baby. The fetus adapts to undernutrition by changing its metabolism, altering its production of hormones and the sensitivity of tissues to them, redistributing its blood flow, and slowing its growth rate. In some circumstances, the placenta may enlarge. Adaptations to undernutrition that occur during development permanently alter the structure and function of the body.
引用
收藏
页码:69 / 88
页数:20
相关论文
共 120 条
  • [1] PREPREGNANCY WEIGHT, WEIGHT-GAIN, AND BIRTH-WEIGHT
    ABRAMS, BF
    LAROS, RK
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1986, 154 (03) : 503 - 509
  • [2] Alberman E, 1992, Paediatr Perinat Epidemiol, V6, P134, DOI 10.1111/j.1365-3016.1992.tb00755.x
  • [3] [Anonymous], STUDIES UNDER NUTR W
  • [4] [Anonymous], 1975, FAMINE HUM DEV DUTCH
  • [5] CHILDREN BORN DURING THE SIEGE OF LENINGRAD IN 1942
    ANTONOV, AN
    [J]. JOURNAL OF PEDIATRICS, 1947, 30 (03) : 250 - 259
  • [6] BACKSTRAND JR, 1995, LONG TERM CONSEQUENC
  • [7] BAIRD D, 1945, J OBSTET GYN BRIT EM, V52, P217
  • [8] FETAL NUTRITION AND CARDIOVASCULAR-DISEASE IN ADULT LIFE
    BARKER, DJP
    GLUCKMAN, PD
    GODFREY, KM
    HARDING, JE
    OWENS, JA
    ROBINSON, JS
    [J]. LANCET, 1993, 341 (8850) : 938 - 941
  • [9] BEISCHER N A, 1970, Journal of Obstetrics and Gynaecology of the British Commonwealth, V77, P398
  • [10] BJORNTORP P, 1991, INT J OBESITY, V15, P67