SPI-7: Salmonella's Vi-Encoding Pathogenicity Island

被引：32
作者：
Seth-Smith, Helena M. B. [1 ]
机构：
[1] Wellcome Trust Sanger Inst, Pathogen Sequencing Unit, Hinxton CB10 1SA, Cambs, England
来源：
JOURNAL OF INFECTION IN DEVELOPING COUNTRIES | 2008年 / 2卷 / 04期
基金：
英国惠康基金;
关键词：
SPI7; Typhi; typhoid; virulence; PAI; Salmonella;
D O I：
10.3855/jidc.220
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Salmonella Pathogenicity Island-7 (SPI-7) is a large, mosaic, genetic island, found in several serovars of Salmonella enterica subsp. enterica associated with systemic disease. As well as encoding genes which may aid its own transmission, it carries genes for potential virulence factors such as Vi antigen, SopE effector and type IVB pili. The stability of SPI-7 is of interest with respect to typhoid fever and related vaccines.
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收藏
页码：267 / 271
页数：5
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