Uncatalyzed Knoevenagel condensation in PEG-600 at room temperature

被引:20
作者
Bandgar, Babasaheb P. [1 ]
Korbad, Balaji L. [1 ]
Patil, Sachin A. [1 ]
Bandgar, Sunita B. [1 ]
Chavan, Hemant V. [1 ]
Hote, Baliram S. [1 ]
机构
[1] Swami Ramanand Teerth Marathwada Univ, Sch Chem Sci, Organ Chem Res Lab, Nanded 431606, India
关键词
D O I
10.1071/CH08106
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A rapid, efficient, and ecofriendly protocol has been developed for the Knoevenagel condensation of active methylene compounds with aromatic, aliphatic, conjugated and heteroaromatic aldehydes in polyethylene glycol-600 (PEG-600) with good to excellent yields.
引用
收藏
页码:700 / 703
页数:4
相关论文
共 35 条
[21]   Tellurium(IV) tetrachloride catalysed facile Knoevenagel reaction [J].
Khan, RH ;
Mathur, RK ;
Ghosh, AC .
SYNTHETIC COMMUNICATIONS, 1996, 26 (04) :683-686
[22]   Solvent-free bentonite-catalyzed condensation of malonic acid and aromatic aldehydes under microwave irradiation [J].
Loupy, A ;
Song, SJ ;
Sohn, SM ;
Lee, YM ;
Kwon, TW .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 2001, (10) :1220-1222
[23]   Uncatalysed reactions in water: Part 2. Preparation of 3-carboxycoumarins [J].
Maggi, R ;
Bigi, F ;
Carloni, S ;
Mazzacani, A ;
Sartori, G .
GREEN CHEMISTRY, 2001, 3 (04) :173-174
[24]   MELDRUMS ACID [J].
MCNAB, H .
CHEMICAL SOCIETY REVIEWS, 1978, 7 (03) :345-358
[25]   Knoevenagel condensation in heterogeneous phase catalyzed by IR radiation and Tonsil Actisil FF [J].
Obrador, E ;
Castro, M ;
Tamaríz, J ;
Zepeda, G ;
Miranda, R ;
Delgado, F .
SYNTHETIC COMMUNICATIONS, 1998, 28 (24) :4649-4663
[26]   Pyridazine derivatives.: Part 21:: Synthesis and structural study of novel 4-aryl-2,5-dioxo-8-phenylpyrido[2,3-d]pyridazines [J].
Pita, B ;
Sotelo, E ;
Suárez, M ;
Raviña, E ;
Ochoa, E ;
Verdecia, Y ;
Novoa, H ;
Blaton, N ;
de Ranter, C ;
Peeters, OM .
TETRAHEDRON, 2000, 56 (16) :2473-2479
[27]  
RAO PS, 1991, TETRAHEDRON LETT, V32, P5821
[28]   LiCl catalyzed Knoevenagel condensation: Comparative study of conventional method vs microwave irradiation [J].
Sabitha, G ;
Reddy, BVS ;
Babu, RS ;
Yadav, JS .
CHEMISTRY LETTERS, 1998, (08) :773-774
[29]   Solvent-free synthesis of 3-carboxycoumarins [J].
Scott, JL ;
Raston, CL .
GREEN CHEMISTRY, 2000, 2 (05) :245-247
[30]   Solvent replacement for green processing [J].
Sherman, J ;
Chin, B ;
Huibers, PDT ;
Garcia-Valls, R ;
Hatton, TA .
ENVIRONMENTAL HEALTH PERSPECTIVES, 1998, 106 :253-271