Hypothalamic Control of Sleep in Aging

被引：11

作者：

Rolls, Asya ^{[1
]}

机构：

[1] Stanford Univ, Dept Psychiat & Behav Sci, Stanford, CA 94305 USA

来源：

NEUROMOLECULAR MEDICINE | 2012年 / 14卷 / 03期

关键词：

Sleep; Hypothalamus; Aging; Hypocretin; MELANIN-CONCENTRATING HORMONE; VENTROLATERAL PREOPTIC NUCLEUS; AGE-RELATED-CHANGES; HISTAMINERGIC TUBEROMAMMILLARY NEURONS; PHASEOLUS-VULGARIS-LEUKOAGGLUTININ; VASOACTIVE-INTESTINAL-PEPTIDE; INTRALAMINAR THALAMIC NUCLEI; WAKING DISCHARGE PATTERNS; OREXIN KNOCKOUT MICE; EYE-MOVEMENT SLEEP;

D O I：

10.1007/s12017-012-8175-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The timing of sleep and its duration are affected by circadian and homeostatic factors. Physiological and behavioral attributes such as the duration of previous wake period, food availability, temperature, and stress all affect sleep and its quality. As many of these physiological inputs are integrated in the hypothalamus, it is not surprising that this brain structure plays a crucial role in the regulation of sleep. I will discuss this role also in the context of aging, which is associated with changes in both hypothalamic function and the composition of sleep.

引用

页码：139 / 153

页数：15

共 174 条

[1] Mechanisms of neuropeptide Y, peptide YY, and pancreatic polypeptide inhibition of identified green fluorescent protein-expressing GABA neurons in the hypothalamic neuroendocrine arcuate nucleus [J].

Acuna-Goycolea, C ;

Tamamaki, N ;

Yanagawa, Y ;

Obata, K ;

van den Pol, AN .

JOURNAL OF NEUROSCIENCE, 2005, 25 (32) :7406-7419

[2] Sleep architecture of the melanin-concentrating hormone receptor 1-knockout mice [J].

Adamantidis, Antoine ;

Salvert, Denise ;

Goutagny, Romain ;

Lakaye, Bernard ;

Gervasoni, Damien ;

Grisar, Thierry ;

Luppi, Pierre-Herve ;

Fort, Patrice .

EUROPEAN JOURNAL OF NEUROSCIENCE, 2008, 27 (07) :1793-1800

[3] Neural substrates of awakening probed with optogenetic control of hypocretin neurons [J].

Adamantidis, Antoine R. ;

Zhang, Feng ;

Aravanis, Alexander M. ;

Deisseroth, Karl ;

De Lecea, Luis .

NATURE, 2007, 450 (7168) :420-U9

[4]

ALLEN LS, 1989, J NEUROSCI, V9, P497

[5] Orexin/Hypocretin and Histamine: Distinct Roles in the Control of Wakefulness Demonstrated Using Knock-Out Mouse Models [J].

Anaclet, Christelle ;

Parmentier, Regis ;

Ouk, Koliane ;

Guidon, Gerard ;

Buda, Colette ;

Sastre, Jean-Pierre ;

Akaoka, Hideo ;

Sergeeva, Olga A. ;

Yanagisawa, Masashi ;

Ohtsu, Hiroshi ;

Franco, Patricia ;

Haas, Helmut L. ;

Lin, Jian-Sheng .

JOURNAL OF NEUROSCIENCE, 2009, 29 (46) :14423-14438

[6] Artificially accelerated aging by shortened photoperiod alters early gene expression (Fos) in the suprachiasmatic nucleus and sulfatoxymelatonin excretion in a small primate, Microcebus murinus [J].

Aujard, F ;

Dkhissi-Benyahya, O ;

Fournier, I ;

Claustrat, B ;

Schilling, A ;

Cooper, HM ;

Perret, M .

NEUROSCIENCE, 2001, 105 (02) :403-412

[7] Activation of a subpopulation of orexin/hypocretin-containing hypothalamic neurons by GABAA receptor-mediated inhibition of the nucleus accumbens shell, but not by exposure to a novel environment [J].

Baldo, BA ;

Gual-Bonilla, L ;

Sijapati, K ;

Daniel, RA ;

Landry, CF ;

Kelley, AE .

EUROPEAN JOURNAL OF NEUROSCIENCE, 2004, 19 (02) :376-386

[8] Opposite effects of noradrenaline and acetylcholine upon hypocretin/orexin versus melanin concentrating hormone neurons in rat hypothalamic slices [J].

Bayer, L ;

Eggermann, E ;

Serafin, M ;

Grivel, J ;

Machard, D ;

Muhlethaler, M ;

Jones, BE .

NEUROSCIENCE, 2005, 130 (04) :807-811

[9] Abnormal Sleep/Wake Dynamics in Orexin Knockout Mice [J].

Behn, Cecilia G. Diniz ;

Klerman, Elizabeth B. ;

Mochizuki, Takatoshi ;

Lin, Shih-Chieh ;

Scammell, Thomas E. .

SLEEP, 2010, 33 (03) :297-306

[10] STIMULATION OF A(1) ADENOSINE RECEPTORS MIMICS THE ELECTROENCEPHALOGRAPHIC EFFECTS OF SLEEP-DEPRIVATION [J].

BENINGTON, JH ;

KODALI, SK ;

HELLER, HC .

BRAIN RESEARCH, 1995, 692 (1-2) :79-85

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