The Relationship Between Some of the Cardiovascular Risk Factors and Arterial Stiffness Parameters in Essentially Hypertensive Patients

被引:24
作者
Altun, Battal [1 ]
Bulucu, Fatih [1 ]
Demirbas, Seref [1 ]
Karaman, Murat [1 ]
Ay, Seyit Ahmet [1 ]
Cakar, Mustafa [1 ]
Apikoglu, Mehmet [1 ]
Saglam, Kenan [1 ]
Demirkol, Sait [2 ]
Balta, Sevket [2 ]
机构
[1] Guflhane Med Acad, Dept Internal Med, Ankara, Turkey
[2] Gulhane Mil Med Acad, Dept Cardiol, Ankara, Turkey
关键词
arterial stiffness; pulse wave velocity; augmentation index; central aortic pressure; hypertension; WORLD-HEALTH-ORGANIZATION; PULSE-WAVE VELOCITY; BLOOD-PRESSURE; INTERNATIONAL-SOCIETY; UNITED-STATES; ALL-CAUSE; MORTALITY; HYPOTHYROIDISM; GUIDELINES; COUNTRIES;
D O I
10.3109/10641963.2012.746354
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Hypertensive patients have strong evidence of endothelial dysfunction. We aimed to explore the relationships between cardiovascular risk factors and arterial stiffness parameters in hypertensive patients. The study population included 109 hypertensive patients (63 females, 46 males). Arterial stiffness measures including pulse wave velocity, augmentation index, and central aortic pressure were applied. Augmentation index and central aortic pressure were found to be significantly higher (P < .001 and P = .03, respectively) in women. The higher augmentation index and central aortic pressure values were observed in women than in men. These data offer new evidences for the role of sex hormones in the pathogenesis of atherosclerosis in women.
引用
收藏
页码:444 / 448
页数:5
相关论文
共 20 条
[1]  
Altun L, 2005, J HYPERTENS, V23, P1817
[2]  
Chalmers J, 1999, CLIN EXP HYPERTENS, V21, P1009
[3]  
Fisher ND., 2005, Harrison's principles of internal medicine 16th Edition, V16th, P1463
[4]   Excess mortality among blacks and whites in the United States [J].
Geronimus, AT ;
Bound, J ;
Waidmann, TA ;
Hillemeier, MM ;
Burns, PB .
NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (21) :1552-1558
[5]   Prognostic value of aortic pulse wave velocity as index of arterial stiffness in the general population [J].
Hansen, TW ;
Staessen, JA ;
Torp-Pedersen, C ;
Rasmussen, S ;
Thijs, L ;
Ibsen, H ;
Jeppesen, J .
CIRCULATION, 2006, 113 (05) :664-670
[6]   Impact of smoking and smoking cessation on arterial stiffness and aortic wave reflection in hypertension [J].
Jatoi, Noor A. ;
Jerrard-Dunne, Paula ;
Feely, John ;
Mahmud, Azra .
HYPERTENSION, 2007, 49 (05) :981-985
[7]   Blood pressure as a cardiovascular risk factor - Prevention and treatment [J].
Kannel, WB .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1996, 275 (20) :1571-1576
[8]  
Klein I., 2000, Werner and Ingbar's The Thyroid: A fundamental and clinical text book, V8th edi, P777
[9]   Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients [J].
Laurent, S ;
Boutouyrie, P ;
Asmar, R ;
Gautier, I ;
Laloux, B ;
Guize, L ;
Ducimetiere, P ;
Benetos, A .
HYPERTENSION, 2001, 37 (05) :1236-1241
[10]   HIGH-NORMAL BLOOD-PRESSURE PROGRESSION TO HYPERTENSION IN THE FRAMINGHAM HEART-STUDY [J].
LEITSCHUH, M ;
CUPPLES, LA ;
KANNEL, W ;
GAGNON, D ;
CHOBANIAN, A .
HYPERTENSION, 1991, 17 (01) :22-27