Terpenoids from the roots of Drypetes hoaensis and their cytotoxic activities

被引：10
作者：
Wittayalai, Sawangjitt [1 ]
Mahidol, Chulabhorn [1 ,2 ,3 ]
Prachyawarakorn, Vilailak [1 ]
Prawat, Hunsa [1 ]
Ruchirawat, Somsak [1 ,2 ,3 ]
机构：
[1] Chulabhorn Res Inst, Bangkok 10210, Thailand
[2] EHT, Chulabhorn Grad Inst, Bangkok 10210, Thailand
[3] EHT, Ctr Environm Hlth & Toxicol, Bangkok 10210, Thailand
来源：
PHYTOCHEMISTRY | 2014年 / 99卷
关键词：
Dypetes hoaensis; Euphorbiaceae; Roots; Eremophilane; Eudesmane; Friedelane; Lignan; Steroid; Cytotoxicities; PHENYLPROPANOID GLYCOSIDES; COLORIMETRIC ASSAY; CONSTITUENTS;
D O I：
10.1016/j.phytochem.2013.12.017
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Seven terpenoids consisting of five sesquiterpenoids, hoaensieremone, hoaensieremodione, hoaensifuranonal, hoaensieudesone, and hoaensibenzofuranal, and two friedelane triterpenoids, 3 alpha-(E)-p-coumaroyloxyfriedelan-7-one and 3 alpha-(E)-caffeoyloxyfriedelan-7-one were isolated from the dichloromethane extract of the roots of Drypetes hoaensis, Additionally, twelve known compounds and vanillin were isolated. Their structures were established on the basis of spectroscopic analysis, as well as by comparison with literature data. The anticancer activity of nine of these compounds was investigated. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：121 / 126
页数：6
相关论文
共 25 条
  • [1] Phytochemistry and antifungal properties of the newly discovered tree Pleodendron costaricense
    Amiguet, Virginie Treyvaud
    Petit, Philippe
    Ta, Chieu Anh
    Nunez, Ronaldo
    Sanchez-Vindas, Pablo
    Alvarez, Luis Poveda
    Smith, Myron L.
    Arnason, John Thor
    Durst, Tony
    [J]. JOURNAL OF NATURAL PRODUCTS, 2006, 69 (07): : 1005 - 1009
  • [2] Triterpenoids with antimicrobial activity from Drypetes inaequalis
    Awanchiri, Simon Suh
    Trinh-Van-Dufat, Hanh
    Shirri, Jovita Chi
    Dongfack, Marlise Diane J.
    Nguenang, Guy Merlin
    Boutefnouchet, Sabrina
    Fomum, Zacharias T.
    Seguin, Elisabeth
    Verite, Philippe
    Tillequin, Francois
    Wandji, Jean
    [J]. PHYTOCHEMISTRY, 2009, 70 (03) : 419 - 423
  • [3] SESQUITERPENOIDS OF WARBURGIA SPECIES .I. WARBURGIN AND WARBURGIADIONE
    BROOKS, CJW
    DRAFFAN, GH
    [J]. TETRAHEDRON, 1969, 25 (14) : 2865 - &
  • [4] CARMICHAEL J, 1987, CANCER RES, V47, P936
  • [5] Charles J.P., 1993, ALDRICH LIB 13C 1H F, V2, p[959A, 966C]
  • [6] Phenylpropanoid glycosides from Smilax glabra
    Chen, T
    Li, JX
    Xu, Q
    [J]. PHYTOCHEMISTRY, 2000, 53 (08) : 1051 - 1055
  • [7] FURTHER INVESTIGATION OF GRAPEFRUIT JUICE FLAVOR COMPONENTS (CITRUS-PARADISI MACFAYDEN) - VALENCANE-TYPE AND EUDESMANE-TYPE SESQUITERPENE KETONES
    DEMOLE, E
    ENGGIST, P
    [J]. HELVETICA CHIMICA ACTA, 1983, 66 (05) : 1381 - 1391
  • [8] Doyle A., 1997, MAMMALIAN CELL CULTU, P47
  • [9] A NEW SPRAY REAGENT FOR PAPER CHROMATOGRAPHY OF POLYOLS AND CETOSES
    GODIN, P
    [J]. NATURE, 1954, 174 (4420) : 134 - 134
  • [10] Gohari AR, 2011, DARU, V19, P74
123