Diabetes ketoacidosis in pregnancy

被引:40
作者
de Veciana, Margarita [1 ]
机构
[1] Eastern Virginia Med Sch, Norfolk, VA 23507 USA
关键词
Diabetes diabetic pregnancy; Ketoacidosis review management; BLOOD-GLUCOSE LEVELS; MANAGEMENT; PATHOPHYSIOLOGY; SYSTEM;
D O I
10.1053/j.semperi.2013.04.005
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Diabetic ketoacidosis (DKA) is a serious medical and obstetrical emergency usually occurring in patients with type 1 (insulin-dependent) diabetes mellitus. Although modern management of the patient with diabetes should prevent the occurrence of DKA during pregnancy, this complication still occurs and can result in significant morbidity and mortality for mother and/or fetus. Metabolic changes occurring during pregnancy can predispose a pregnant diabetic to DKA. The diagnosis of DKA can be more challenging during pregnancy as it does not always manifest with the classic presenting symptoms or laboratory findings. In fact, although uncommon, during pregnancy, DKA may develop even in the setting of relative normoglycemia. Prompt diagnosis and management is essential in order to optimize maternal and fetal outcomes. This article will provide the reader with information regarding the pathophysiology underlying DKA complicating pregnancy and will provide practical management guidelines for the diagnosis and management of this condition. (c) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:267 / 273
页数:7
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