Transcriptional activation - Something new to hang your HAT on

被引：48
|
作者：
Montminy, M
机构：
[1] Section on Molecular Biology,
[2] Joslin Diabetes Center,undefined
[3] One Joslin Place,undefined
来源：
NATURE | 1997年 / 387卷 / 6634期
关键词：
D O I：
10.1038/42594
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The binding of a hormone to a so-called nuclear hormone receptor can engage a cell's transcriptional apparatus, and the end result is transcription in response to production of the hormone. But how does this occur? Two groups have now come a step closer to answering this question — they have identified a small, peptide motif that mediates the interaction between nuclear hormone receptors and the transcriptional apparatus
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页码：654 / 655
页数：2
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