Effects of Compounds Isolated from the Fruits of Rumex japonicus on the Protein Glycation

被引：19
作者：
Jang, Dae Sik [1 ]
Kim, Jong Min [1 ]
Kim, Junghyun [1 ]
You, Jeong Lim [1 ]
Kim, Young Sook [1 ]
Kim, Jin Sook [1 ]
机构：
[1] Korea Inst Oriental Med, Dept Herbal Pharmaceut Dev, Taejon 305812, South Korea
来源：
CHEMISTRY & BIODIVERSITY | 2008年 / 5卷 / 12期
关键词：
D O I：
10.1002/cbdv.200890226
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
An anthraquinone, emodin (1), and five flavonoids, kaempferol-3-O-beta-D-glucoside (2), quercetin (3), quercitrin (4). isoquercitrin (5), and (+)-catechin (6), were isolated from an AcOEt-soluble extract of the fruits of Rumex japonicus. Their structures were determined by spectroscopic data interpretation. All the isolates were evaluated for their potential to inhibit AGEs (advanced glycation end products) formation and AGEs cross-linking, and to break already formed AGEs cross-links.
引用
收藏
页码：2718 / 2723
页数：6
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