Serotype and Clonal Evolution of Penicillin-Nonsusceptible Invasive Streptococcus pneumoniae in the 7-Valent Pneumococcal Conjugate Vaccine Era in Italy

被引：23

作者：

Gherardi, Giovanni ^{[2
]}

D'Ambrosio, Fabio ^{[1
]}

Visaggio, Daniela ^{[2
]}

Dicuonzo, Giordano ^{[2
]}

Del Grosso, Maria ^{[1
]}

Pantosti, Annalisa ^{[1
]}

机构：

[1] Ist Super Sanita, Dept Infect Parasit & Immune Mediated Dis, I-00161 Rome, Italy

[2] Univ Campus Biomed, Ctr Integrato Ric, Microbiol Lab, Rome, Italy

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2012年 / 56卷 / 09期

关键词：

ANTIBIOTIC-RESISTANCE; DRUG-RESISTANT; DISEASE; 19A; CARRIAGE; CHILDREN; STRAIN;

D O I：

10.1128/AAC.00830-12

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The percentage of invasive penicillin-nonsusceptible pneumococci (PNSSP) isolated in Italy in the seven-valent pneumococcal conjugate vaccine (PCV7) era moderately increased in comparison to the pre-PCV7 era. Increase of nonvaccine serotypes was observed among PNSSP. The most frequent PNSSP clones were the same as those identified in the pre-PCV7 era, although they were present in different proportions. Clonal expansion, emergence of new clones, and acquisition of penicillin resistance by established clones contributed to the maintenance of penicillin resistance.

引用

页码：4965 / 4968

页数：4

共 23 条

[1] Denmark14-230 Clone as an Increasing Cause of Pneumococcal Infection in Portugal within a Background of Diverse Serotype 19A Lineages [J].

Aguiar, Sandra I. ;

Pinto, Francisco R. ;

Nunes, Sonia ;

Serrano, Isa ;

Melo-Cristino, Jose ;

Sa-Leao, Raquel ;

Ramirez, Mario ;

de Lencastre, Herminia .

JOURNAL OF CLINICAL MICROBIOLOGY, 2010, 48 (01) :101-108

[2]

[Anonymous], 0929 ISTISAN ICONA W

[3] Shifting Genetic Structure of Invasive Serotype 19A Pneumococci in the United States [J].

Beall, Bernard W. ;

Gertz, Robert E. ;

Hulkower, Rachel L. ;

Whitney, Cynthia G. ;

Moore, Matthew R. ;

Brueggemann, Angela B. .

JOURNAL OF INFECTIOUS DISEASES, 2011, 203 (10) :1360-1368

[4] Vaccine escape recombinants emerge after pneumococcal vaccination in the united states [J].

Brueggemann, Angela B. ;

Pai, Rekha ;

Crook, Derrick W. ;

Beall, Bernard .

PLOS PATHOGENS, 2007, 3 (11) :1628-1636

[5] Streptococcus pneumoniae serotype 19A in children, South Korea [J].

Choi, Eun Hwa ;

Kim, So Hee ;

Eun, Byung Wook ;

Kim, Sun Jung ;

Kim, Nam Hee ;

Lee, Jina ;

Lee, Hoan Jong .

EMERGING INFECTIOUS DISEASES, 2008, 14 (02) :275-281

[6]

Clinical and Laboratory Standards Institute, 2010, M100 S20

[7] Population structure of invasive Streptococcus pneumoniae isolates in Italy prior to the implementation of the 7-valent conjugate vaccine (1999-2003) [J].

Gherardi, G. ;

D'Ambrosio, F. ;

Monaco, M. ;

Camilli, R. ;

Florio, L. De ;

D'Ancona, F. ;

Dicuonzo, G. ;

Pantosti, A. .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2009, 28 (01) :99-103

[8] Antibiotic-resistant invasive pneumococcal clones in Italy [J].

Gherardi, Giovanni ;

Fallico, Loredana ;

Del Grosso, Maria ;

Bonanni, Federica ;

D'Ambrosio, Fabio ;

Manganelli, Riccardo ;

Palu, Giorgio ;

Dicuonzo, Giordano ;

Pantosti, Annalisa .

JOURNAL OF CLINICAL MICROBIOLOGY, 2007, 45 (02) :306-312

[9] Diversity and antibiotic resistance among nonvaccine serotypes of Streptococcus pneumoniae carriage isolates in the post-heptavalent conjugate vaccine era [J].

Hanage, William P. ;

Huang, Susan S. ;

Lipsitch, Marc ;

Bishop, Cynthia J. ;

Godoy, Daniel ;

Pelton, Stephen I. ;

Goldstein, Richard ;

Huot, Heather ;

Finkelstein, Jonathan A. .

JOURNAL OF INFECTIOUS DISEASES, 2007, 195 (03) :347-352

[10] Which pneumococcal serogroups cause the most invasive disease: Implications for conjugate vaccine formulation and use, part I [J].

Hausdorff, WP ;

Bryant, J ;

Paradiso, PR ;

Siber, GR .

CLINICAL INFECTIOUS DISEASES, 2000, 30 (01) :100-121

← 1 2 3 →