Liver Transplant for Cholestatic Liver Diseases

被引:12
作者
Carrion, Andres F. [1 ]
Bhamidimarri, Kalyan Ram [2 ]
机构
[1] Univ Miami, Miller Sch Med, Dept Med, Div Gastroenterol, Miami, FL 33136 USA
[2] Univ Miami, Miller Sch Med, Dept Med, Div Hepatol, Miami, FL 33136 USA
关键词
Cholestatic liver disease; Primary sclerosing cholangitis; Primary biliary cirrhosis; Liver transplantation; Recurrence; Outcomes; PRIMARY SCLEROSING CHOLANGITIS; PRIMARY BILIARY-CIRRHOSIS; CYSTIC-FIBROSIS; RISK-FACTORS; CAROLIS-DISEASE; INTESTINAL FAILURE; ULCERATIVE-COLITIS; MELD EXCEPTION; ATRESIA; RECURRENCE;
D O I
10.1016/j.cld.2012.12.005
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Liver Transplant for Cholestatic Liver Diseases Andres F. Carrion and Kalyan Ram Bhamidimarri Cholestatic liver diseases include a group of diverse disorders with different epidemiology, pathophysiology, clinical course, and prognosis. Despite significant advances in the clinical care of patients with cholestatic liver diseases, liver transplant (LT) remains the only definitive therapy for end-stage liver disease, regardless of the underlying cause. As per the United Network for Organ Sharing database, the rate of cadaveric LT for cholestatic liver disease was 18% in 1991, 10% in 2000, and 7.8% in 2008. This review summarizes the available evidence on various common and rare cholestatic liver diseases, disease-specific issues, and pertinent aspects of LT.
引用
收藏
页码:345 / +
页数:16
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