Synthesis and tuberculostatic activity of functionalized pyrazoles derived from (trifluoromethyl)pyrazole containing a hydrazone group

被引：12

作者：

Bazhin, Denis N. ^{[1
,2
]}

Kudyakova, Yulia S. ^{[1
]}

Onoprienko, Aleksandra Ya. ^{[2
]}

Slepukhin, Pavel A. ^{[1
,2
]}

Burgart, Yanina V. ^{[1
]}

Saloutin, Victor I. ^{[1
]}

机构：

[1] Russian Acad Sci, Ural Branch, Postovsky Inst Organ Synth, 20 S Kovalevskoi 20 Akademicheskaya St, Ekaterinburg 620990, Russia

[2] Ural Fed Univ, 19 Mira St, Ekaterinburg 620002, Russia

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2017年 / 53卷 / 12期

基金：

俄罗斯基础研究基金会;

关键词：

hydrazones; pyrazole; thiosemicarbazides; condensation;

D O I：

10.1007/s10593-018-2214-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The condensation of 5-(1-hydrazinylideneethyl)-3-(trifluoromethyl)-1H-pyrazole with trimethyl orthoacetate, dimethylformamide dimethyl acetal, and aryl thioisocyanates resulted in a series of functionalized pyrazoles and their tuberculostatic activity was studied.

引用

页码：1324 / 1329

页数：6

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