Current Status and Future Directions of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Ovarian Cancer

被引：46
作者：
Helm, C. William [1 ]
机构：
[1] St Louis Univ, Sch Med, Div Gynecol Oncol, Dept Obstet Gynecol & Womens Hlth, St Louis, MO 63117 USA
来源：
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2012年 / 21卷 / 04期
关键词：
Ovarian cancer; Epithelial ovarian cancer; Intraperitoneal chemotherapy; HIPEC; Hyperthermia; Hyperthermic intraperitoneal chemotherapy; GYNECOLOGIC-ONCOLOGY-GROUP; PEGYLATED LIPOSOMAL DOXORUBICIN; LONG-TERM SURVIVAL; DNA DAMAGE RESPONSES; PHASE-II TRIAL; PERITONEAL CARCINOMATOSIS; NEOADJUVANT CHEMOTHERAPY; STAGE-III; FOLLOW-UP; SECONDARY CYTOREDUCTION;
D O I：
10.1016/j.soc.2012.07.007
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Epithelial ovarian cancer is a peritoneal surface malignancy that most often presents with spread of disease within the peritoneal cavity. Overall 5-year survival is around 50% and progress in improving outcomes is slow. Among other areas of research, hyperthermic intraperitoneal chemotherapy (HIPEC) provides a promising option. This article reviews the current status of treatment of epithelial ovarian cancer, experience with HIPEC to date, and future directions.
引用
收藏
页码：645 / +
页数：20
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