Recent developments in isocyanide based multicomponent reactions in applied chemistry

被引：4184
作者：
Dömling, A [1 ]
机构：
[1] ABC Pharm, D-81243 Munich, Germany
来源：
CHEMICAL REVIEWS | 2006年 / 106卷 / 01期
关键词：
D O I：
10.1021/cr0505728
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Multicomponent reactions (MCRs) are reactions where more than two starting materials react to form a product, incorporating all of the atoms of the educts. These reactions are classified according to the reaction mechanisms, the components involved, or their intrinsic variability. This paper discusses stereocontrol in MCRs, novel isocyanide based MCRs (IMCRs), applications of MCRs in drug discovery, MCRs in natural product synthesis, and miscellaneous applications of IMCRs.
引用
收藏
页码：17 / 89
页数：73
相关论文
共 50 条
[21]   Synthesis of Lactams via Isocyanide-Based Multicomponent Reactions [J].
Pharande, Shrikant G. .
SYNTHESIS-STUTTGART, 2021, 53 (03) :418-446
[22]   Piperazine Scaffolds via Isocyanide-Based Multicomponent Reactions [J].
Doemling, Exander ;
Huang, Yijun .
SYNTHESIS-STUTTGART, 2010, (17) :2859-2883
[23]   An Update on Isocyanide-Based Multicomponent Reactions in Polymer Science [J].
Llevot, Audrey ;
Boukis, Andreas C. ;
Oelmann, Stefan ;
Wetzel, Katharina ;
Meier, Michael A. R. .
TOPICS IN CURRENT CHEMISTRY, 2017, 375 (04)
[24]   An Update on Isocyanide-Based Multicomponent Reactions in Polymer Science [J].
Audrey Llevot ;
Andreas C. Boukis ;
Stefan Oelmann ;
Katharina Wetzel ;
Michael A. R. Meier .
Topics in Current Chemistry, 2017, 375
[25]   Isocyanide-Based Multicomponent Reactions of Free Phenylboronic Acids [J].
Neochoritis, Constantinos G. ;
Zarganes-Tzitzikas, Tryfon ;
Novotna, Michaela ;
Mitrikova, Tatiana ;
Wang, Zefeng ;
Kurpiewska, Katarzyna ;
Kalinowska-Tluscik, Justyna ;
Domling, Alexander .
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2019, 2019 (35) :6132-6137
[26]   Isocyanide based multi component reactions in combinatorial chemistry [J].
Dömling, A .
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 1998, 1 (01) :1-22
[27]   Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids [J].
Barreto, Angelica de Fatima S. ;
Vercillo, Otilie E. ;
Wessjohann, Ludger A. ;
Andrade, Carlos Kleber Z. .
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2014, 10 :1017-1022
[28]   Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics [J].
Koopmanschap, Gijs ;
Ruijter, Eelco ;
Orru, Romano V. A. .
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2014, 10 :544-598
[29]   Catalytic Enantioselective Isocyanide-Based Reactions: Beyond Passerini and Ugi Multicomponent Reactions [J].
Luo, Jian ;
Chen, Guo-Shu ;
Chen, Shu-Jie ;
Li, Zhao-Dong ;
Liu, Yun-Lin .
CHEMISTRY-A EUROPEAN JOURNAL, 2021, 27 (22) :6598-6619
[30]   Multicomponent multicatalyst reactions (MC)2R: Recent developments [J].
Lautens, Mark .
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
12345