Development of a versatile confocal Raman microscope

被引：2
|
作者：
Alcock, RD
Dickinson, MR
King, TA
机构：
来源：
BIOMEDICAL SYSTEMS AND TECHNOLOGIES, PROCEEDINGS OF | 1996年 / 2928卷
关键词：
D O I：
10.1117/12.259966
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A versatile confocal microscope has been developed that combines the optical sectioning properties of a confocal microscope with the chemical identification characteristics offered by Raman spectroscopy to yield a high performance imaging instrument. The apparatus is described and general alignment procedures discussed for optimum performance. An axial resolution of 1.8 mu m has been determined experimentally for a Raman active planar structure and its form compared to theory. A broad range of applications are envisaged in areas of biology, geology and other areas of microscopic analysis. A study is presented showing its applicability to photodynamic therapy for the localisation of specific dyes within cells.
引用
收藏
页码：238 / 247
页数：10
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