Dysnatremias in Patients With Kidney Disease

被引：59

作者：

Combs, Sara ^{[1
]}

Berl, Tomas ^{[1
]}

机构：

[1] Univ Colorado, Div Renal Dis & Hypertens, Aurora, CO 80230 USA

来源：

AMERICAN JOURNAL OF KIDNEY DISEASES | 2014年 / 63卷 / 02期

关键词：

Hyponatremia; hypernatremia; chronic kidney disease; end-stage renal disease; CHRONIC-RENAL-FAILURE; UNIT-ACQUIRED HYPONATREMIA; DIALYSATE SODIUM; MAINTENANCE HEMODIALYSIS; PERITONEAL-DIALYSIS; VASOPRESSIN; HYPERNATREMIA; MORTALITY; RISK; PRESCRIPTION;

D O I：

10.1053/j.ajkd.2013.09.017

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Dysnatremias are among the most common electrolyte disorders in clinical medicine. Recent studies have shown that individuals with chronic kidney disease also are afflicted by these electrolyte disorders. Furthermore, their presence imparts an increased risk of mortality. In this review, we discuss studies in experimental animals and in humans that have attempted to establish the mechanisms responsible for limiting urinary dilution and urinary concentration in progressive kidney disease. The clinical implications of these disorders in water excretion are discussed in the setting of optimal water intake as kidney disease progresses. This review emphasizes the management of patients with chronic kidney disease who have marked abnormalities in serum sodium concentrations and gives specific recommendations for modifications in renal replacement therapy prescription in hyponatremic patients with end-stage renal disease. (C) 2014 by the National Kidney Foundation, Inc.

引用

页码：294 / 303

页数：10

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