Specific nucleic acid detection based on fluorescent light-up probe from fluorogens with aggregation-induced emission characteristics

被引：52

作者：

Li, Yuqiong ^{[1
]}

Kwok, Ryan T. K. ^{[2
]}

Tang, Ben Zhong ^{[1
,2
,3
]}

Liu, Bin ^{[1
,4
]}

机构：

[1] Inst Mat Res Engn, 3 Res Link, Singapore 117602, Singapore

[2] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China

[3] S China Univ Technol, SCUT HKUST Joint Res Lab, Guangdong Innovat Res Team, State Key Lab Luminescent Mat & Devices, Guangzhou 510640, Guangdong, Peoples R China

[4] Natl Univ Singapore, Dept Chem & Biomol Engn, Singapore 117567, Singapore

来源：

RSC ADVANCES | 2013年 / 3卷 / 26期

基金：

新加坡国家研究基金会;

关键词：

DNA; HYBRIDIZATION;

D O I：

10.1039/c3ra41983e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a new fluorescent light-up probe design strategy by conjugating fluorogens with aggregation-induced emission (AIE) characteristics, e.g. tetraphenylethene with a single-stranded oligonucleotide for homogeneous specific complementary DNA detection in solution.

引用

页码：10135 / 10138

页数：4

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