Stereoselective synthesis of (E)-α,β-unsaturated esters via carbene-catalyzed redox esterification

被引：251
作者：
Zeitler, K [1 ]
机构：
[1] Univ Regensburg, Inst Organ Chem, D-93053 Regensburg, Germany
来源：
ORGANIC LETTERS | 2006年 / 8卷 / 04期
关键词：
D O I：
10.1021/ol052826h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Stereoselective, carbene-mediated redox esterification of alkynyl aldehydes provides mild and atom economical access to (E)-configurated, alpha,beta-unsaturated carboxylic esters. The organocatalytic method relies on the generation of activated carboxylates via extended/conjugated umpolung in the presence of catalytic amounts of carbene precursor and base.
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收藏
页码：637 / 640
页数：4
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