Biomarkers in uterine leiomyoma

被引：31

作者：

Levy, Gary ^{[1
]}

Hill, Micah J. ^{[1
]}

Plowden, Torie C. ^{[2
]}

Catherino, William H. ^{[1
,3
]}

Armstrong, Alicia Y. ^{[1
]}

机构：

[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Program Reprod & Adult Endocrinol, NIH, Bethesda, MD 20892 USA

[2] Bayne Jones Army Community Hosp, Ft Polk, LA USA

[3] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA

来源：

FERTILITY AND STERILITY | 2013年 / 99卷 / 04期

基金：

美国国家卫生研究院;

关键词：

Leiomyoma; fibroids; biomarker; EPITHELIAL OVARIAN-CANCER; SERUM CA 125; TRANSVAGINAL SONOGRAPHY; DIFFERENTIAL-DIAGNOSIS; PELVIC MASS; HLA-G; GROWTH; FIBROIDS; MYOMAS; RECEPTOR;

D O I：

10.1016/j.fertnstert.2012.10.048

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Biomarkers are biologic compounds that are easily accessible and reflect normal physiology or pathology. They are useful in a variety of clinical situations that involve detection of subclinical disease, risk stratification, preoperative planning, and monitoring treatment. A useful intervention needs to exist for a biomarker to be an effective tool. Many compounds have been investigated as potential biomarkers for the diagnosis and surveillance of uterine leiomyomas. Most of these compounds demonstrate subtle differences among patients when leiomyomas are compared with controls. The compounds investigated lack the diagnostic accuracy necessary to add any benefit to the current available modalities used to diagnose and monitor uterine leiomyomas. (Fertil Steril (R) 2013;99:1146-52. (C) 2013 by American Society for Reproductive Medicine.)

引用

页码：1146 / 1152

页数：7

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