Development and Characterisation of a 3D Tri-Culture Model of Normal Breast as a Tool for Cancer Initiation Studies Shows Overexpression of Her2 and Her3 Alters 3D Epithelial Architecture

被引：0

作者：

Nash, C. E. ^{[1
]}

Holliday, D. L. ^{[1
]}

Mavria, G. ^{[1
]}

Tomlinson, D. ^{[1
]}

Hanby, A. ^{[1
]}

Berditchevski, F. ^{[2
]}

Speirs, V. ^{[1
]}

机构：

[1] Univ Leeds, Leeds, W Yorkshire, England

[2] Univ Birmingham, Birmingham, W Midlands, England

来源：

JOURNAL OF PATHOLOGY | 2013年 / 231卷

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：14 / 14

页数：1

共 50 条

[21] Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab [J].

M Pickl ;

C H Ries .

Oncogene, 2009, 28 :461-468

[22] HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment [J].

Weigelt, Britta ;

Lo, Alvin T. ;

Park, Catherine C. ;

Gray, Joe W. ;

Bissell, Mina J. .

BREAST CANCER RESEARCH AND TREATMENT, 2010, 122 (01) :35-43

[23] HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment [J].

Britta Weigelt ;

Alvin T. Lo ;

Catherine C. Park ;

Joe W. Gray ;

Mina J. Bissell .

Breast Cancer Research and Treatment, 2010, 122 :35-43

[24] Developing 3D subtyping model for breast cancer patients based on absolute quantitation or ER, PR and Her2 at protein level [J].

Zhang, Jiandi .

CANCER RESEARCH, 2020, 80 (04)

[25] Bioengineering a humanized 3D tri-culture osteosarcoma model to assess tumor invasiveness and therapy response [J].

Monteiro, Catia F. ;

Custodio, Catarina A. ;

Mano, Joao F. .

ACTA BIOMATERIALIA, 2021, 134 :204-214

[26] Development of a novel 3D cancer model by cultivation of malignant effusions in a 3D cell culture system [J].

Amann, Arno ;

Zwierzina, Marit ;

Huber, Julia M. ;

Gamerith, Gabriele ;

Koeck, Stefan ;

Bitsche, Mario ;

Lorenz, Edith ;

Zwierzina, Heinz .

CANCER RESEARCH, 2015, 75

[27] The 3D genomic landscape of differential response to EGFR/HER2 inhibition in endocrine-resistant breast cancer cells [J].

Yang, Yini ;

Choppavarapu, Lavanya ;

Fang, Kun ;

Naeini, Alireza S. ;

Nosirov, Bakhtiyor ;

Li, Jingwei ;

Yang, Ke ;

He, Zhijing ;

Zhou, Yufan ;

Schiff, Rachel ;

Li, Rong ;

Hu, Yanfen ;

Wang, Junbai ;

Jin, Victor X. .

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 2020, 1863 (11)

[28] 3D CULTURE OF HER2 OVER-EXPRESSING BREAST CANCER CELLS PROMOTES AKT TO MAPK PATHWAY SWITCHING AND LOSS OF RESPONSE TO THERAPY [J].

Barrett-Lee, Peter J. ;

Gangadhara, Sharath ;

Smith, Christopher ;

Hiscox, Stephen .

ANTICANCER RESEARCH, 2015, 35 (07) :4292-4293

[29] Development and characterisation of a novel 3D in vitro model of obesity-associated breast cancer as a tool for drug testing [J].

Blyth, Rhianna R. R. ;

Laversin, Stephanie A. ;

Foxall, Russell B. ;

Savva, Constantinos ;

Copson, Ellen ;

Cutress, Ramsey I. ;

Birts, Charles N. ;

Beers, Stephen A. .

NPJ BREAST CANCER, 2025, 11 (01)

[30] Establishing a 3D Vascularized Tri-Culture Model of the Human Airways via a Digital Light Processing Bioprinter [J].

Phogat, Sakshi ;

Guo, Tony Ju Feng ;

Thiam, Fama ;

Osei, Emmanule Twumasi .

BIOTECHNOLOGY AND BIOENGINEERING, 2025, 122 (08) :2273-2280

← 1 2 3 4 5 →