Bacteriology of hidradenitis suppurativa/acne inversa: A review

被引：61

作者：

Nikolakis, Georgios ^{[1
,2
,3
,4
,5
]}

Join-Lambert, Olivier ^{[6
,7
,8
,10
]}

Karagiannidis, Ioannis ^{[1
,2
,3
,4
,5
]}

Guet-Revillet, Helene ^{[6
,7
,8
,10
]}

Zouboulis, Christos C. ^{[1
,2
,3
,4
,5
]}

Nassif, Aude ^{[5
,9
,10
]}

机构：

[1] Dessau Med Ctr, Dept Dermatol, D-06847 Dessau, Germany

[2] Dessau Med Ctr, Dept Venereol, D-06847 Dessau, Germany

[3] Dessau Med Ctr, Dept Allergol, D-06847 Dessau, Germany

[4] Dessau Med Ctr, Dept Immunol, D-06847 Dessau, Germany

[5] European Hidradenitis Suppurat Fdn eV, Dessau, Germany

[6] Hop Necker Enfants Malad, AP HP, Lab Clin Microbiol, Paris, France

[7] Univ Paris 05, Sorbonne Paris Cite, Paris, France

[8] INSERM, U1151, Equipe Physiopathol Infect Syst 11, Paris, France

[9] Inst Pasteur, Ctr Med, Serv Pathol Infect & Trop, Paris, France

[10] Ctr Infectiol Necker Pasteur, Paris, France

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2015年 / 73卷 / 05期

关键词：

acne inversa; actinomycetes; anaerobes; bacterial metagenomics; bacteriology; biofilm; hidradenitis suppurativa; milleri group streptococci; Staphylococcus lugdunensis; ANTIMICROBIAL PEPTIDES; ACNE INVERSA; INNATE; MICROBIOLOGY; COLONIZATION; INFECTIONS; EXPRESSION; ABSCESSES; CULTURES; MILLERI;

D O I：

10.1016/j.jaad.2015.07.041

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Given that follicular papules and pustules, as well as nodules and abscesses, are the clinical hallmarks of hidradenitis suppurativa (HS), an infectious, bacterial pathway has been suspected in the pathogenesis of this chronic, inflammatory condition. Elucidating the behavior and role of bacterial species in HS and their interaction with cutaneous innate immunity will provide more insight into the pathophysiology of this condition. This review of prospective investigations suggests a synergistic relationship between impaired innate immunity and microbial factors in the etiology of HS.

引用

页码：S12 / S18

页数：7

共 41 条

[1] Acne Inversa: Evaluating Antimicrobial Peptides and Proteins [J].