α-hydroxy carboxylic acids:: new ligands for diethylzinc additions to aldehydes

被引：16

作者：

Bauer, T ^{[1
]}

Tarasiuk, J ^{[1
]}

机构：

[1] Warsaw Univ, Dept Chem, PL-02093 Warsaw, Poland

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 04期

关键词：

diethylzinc; titanium tetraisopropoxide; alpha-hydroxy acid; benzaldehyde; enantioselective;

D O I：

10.1016/S0040-4039(01)02220-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first examples of the enantioselcetive titanium-mediated diethylzinc additions to benzaldehyde catalyzed by optically active alpha-hydroxy acids are presented. (S)-1-Phenylpropanol has been obtained in up to 86% enantiomeric excess. (C) 2002 Elsevier Science Ltd. All rights reserved.

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收藏

页码：687 / 689

页数：3

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