Microbial Origins of Chronic Diseases

被引：18
作者：
Gargano, Lisa M. [1 ]
Hughes, James M. [1 ]
机构：
[1] Emory Univ, Sch Med, Dept Med, Div Infect Dis, Atlanta, GA 30322 USA
来源：
ANNUAL REVIEW OF PUBLIC HEALTH, VOL 35 | 2014年 / 35卷
关键词：
epidemiology; microbiome; etiology; infection; causality; WEST-NILE-VIRUS; CHLAMYDIA-PNEUMONIAE INFECTION; INFLAMMATORY-BOWEL-DISEASE; HUMAN-PAPILLOMAVIRUS TYPES; SQUAMOUS-CELL CARCINOMAS; PERIODONTAL-DISEASE; PRENATAL EXPOSURE; CROHNS-DISEASE; FOLLOW-UP; HEPATOCELLULAR-CARCINOMA;
D O I：
10.1146/annurev-publhealth-032013-182426
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Chronic diseases such as cardiovascular disease and cancer are among the leading causes of death worldwide and have been on the rise over the past decade. Associations between microbial agents and development of chronic diseases have been made in the past, and new connections are currently being assessed. Investigators are examining the relationship between infectious agents and chronic disease using new technologies with more rigor and specificity. This review examines microbial agents' links to and associations with cardiovascular diseases, cancer, neurodegenerative diseases, renal diseases, psychiatric disorders, and obesity and addresses the important role of the human microbiome in maintenance of health and its potential role in chronic diseases. These associations and relationships will impact future research priorities, surveillance approaches, treatment strategies, and prevention programs for chronic diseases.
引用
收藏
页码：65 / 82
页数：18
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