PREDICTIVE SIGNIFICANCE OF A COMPLEX APPROACH IN DETERMINING THE VASCULAR WALL STIFFNESS PARAMETERS IN PATIENTS WITH ARTERIAL HYPERTENSION AND IN PATIENTS WITH ARTERIAL HYPERTENSION AFTER ISCHEMIC STROKE

被引：0

作者：

Kindaliova, V. G. ^{[1
]}

Pronko, T. P. ^{[1
]}

Dobrodey, M. A. ^{[1
]}

Gubkin, S., V ^{[2
]}

机构：

[1] Grodno State Med Univ, 80 Gorky Str, Grodno 230009, BELARUS

[2] Natl Acad Sci Belarus, Inst Physiol, 28 Akad Skaya Str, Minsk 220072, BELARUS

来源：

DOKLADY NATSIONALNOI AKADEMII NAUK BELARUSI | 2022年 / 66卷 / 05期

关键词：

arterial stiffness; prognosis; arterial hypertension; ischemic stroke; RISK;

D O I：

10.29235/1561-8323-2022-66-5-525-532

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The article presents the information about the predictive significance of a complex approach in determining vascular wall stiffness parameters. A total of 159 people with arterial hypertension (AH) and AH after a previous ischemic stroke were examined. A model with a conditional linear predictor (LP) was constructed, using a binary regression equation with a probit-link function for prediction of cardiovascular events. LP is a combination of indicators such as age (A), glomer-ular filtration rate (CKD-EPI), pulse wave velocity (PWV), intima-media thickness (IMT), cardio-ankle vascular index (CAVI) and augmentation index (AI). The equation has the following form: LP = -6.6139 - 0.0978A + 0.031CKD-EPI + 0.0758PWV + 3.2086IMT + 0.4421CAVI + 1.2429AI. The cut-off threshold for LP = 0.0238, sensitivity (Se) 85.71 %, specificity (Sp) 77 % and accuracy (Acc) 78.07 %.

引用

页码：525 / 532

页数：8

共 17 条

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