Screening of spanish medicinal plants for antioxidant and antifungal activities

被引:53
作者
Lopez, Victor [1 ]
Akerreta, Silvia [2 ]
Casanova, Esther [3 ]
Garcia-Mina, Jose Maria [3 ]
Cavero, Rita Yolanda [2 ]
Calvo, Maria Isabel [1 ]
机构
[1] Univ Navarra, Sch Pharm, Dept Pharm & Pharmaceut Technol, E-31080 Pamplona, Spain
[2] Univ Navarra, Sch Pharm, Dept Plant Biol, E-31080 Pamplona, Spain
[3] INABONOS Roullier Grp, R&D Dept, Navarra, Spain
关键词
antifungal; antioxidant; DPPH; medicinal plants; Rhizopus stolonifer;
D O I
10.1080/13880200802179634
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Dichloromethane, ethyl acetate, methanol, and aqueous extracts obtained from 16 Spanish medicinal plants were screened for their antioxidant and antifungal activities. The radical scavenging capacity was evaluated by the DPPH method using a rapid screening by TLC and a spectrophotometric assay. Polar extracts obtained from Jasonia glutinosa L. (Lamiaceae), Tanacetum parthenium (L.) Schultz (Lamiaceae), Equisetum telmateia Ehrh. (Equisetaceae), Verbena officinalis L. (Verbenaceae), and Lythrum salicaria L. (Lythraceae) showed high antioxidant properties. Among them, the methanol extract of Lythrum salicaria showed the strongest antiradical capacity with an IC50 value similar to the positive control ascorbic acid. On the contrary, the best antifungal properties against Rhizopus stolonifer were produced by ethyl acetate or dichloromethane extracts from Anthemis arvensis L. subsp. arvensis (Asteraceae), Tanacetum parthenium, Santolina chamaecyparissus L. subsp. squarrosa Nyman (Asteraceae), Anagallis arvensis L. (Primulaceae) and the methanol extract of Anagallis foemina Miller (Primulaceae). The dichloromethane extract of Anthemis arvensis subsp. arvensis was the best inhibitor of fungus growth.
引用
收藏
页码:602 / 609
页数:8
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