Carbon-Carbon Bond Formation: Palladium-Catalyzed Oxidative Cross-Coupling of N-Tosylhydrazones with Allylic Alcohols

被引：44

作者：

Chen, Huoji ^{[1
]}

Huang, Li ^{[1
]}

Fu, Wei ^{[1
]}

Liu, Xiaohang ^{[1
]}

Jiang, Huanfeng ^{[1
]}

机构：

[1] S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Guangdong, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2012年 / 18卷 / 34期

基金：

中国国家自然科学基金;

关键词：

allylic compounds; C?C coupling; cross-coupling; N-tosylhydrazones; palladium; ALPHA-DIAZOCARBONYL COMPOUNDS; MIGRATORY INSERTION; ARYL HALIDES; CARBENE COMPLEXES; BENZYL BROMIDES; DIAZOESTERS; ARYLATION; REAGENTS; OLEFINS; ESTERS;

D O I：

10.1002/chem.201200949

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the zone: Pd-catalyzed oxidative cross-coupling of N-tosylhydrazones with allylic alcohols leads to C-C bond formation. A palladium-carbene migratory insertion is proposed to play the key role in this transformation. The reaction proceeds with readily available starting materials to afford substituted alkenes in a highly stereoselective manner (see scheme). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：10497 / 10500

页数：4

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