Synthesis of Thermosensitive Glycopolymers Containing D-Glucose Residue: Copolymers with N-isopropylacrylamide

被引：9
作者：
Shinde, Vaishali S. [1 ]
Pawar, Vishwas U. [1 ]
机构：
[1] Univ Pune, Dept Chem, Garware Res Ctr, Pune 411007, Maharashtra, India
来源：
JOURNAL OF APPLIED POLYMER SCIENCE | 2009年 / 111卷 / 05期
关键词：
copolymerization; gel permeation chromatography (GPC); radical polymerization; stimuli-sensitive polymers; water-soluble polymers; GLYCOSAMINOGLYCAN-MIMETIC BIOMATERIALS; FREE-RADICAL POLYMERIZATION; WELL-DEFINED GLYCOPOLYMERS; THERMORESPONSIVE GLYCOPOLYMERS; RAFT POLYMERIZATION; POLYMERS; HYDROGELS; DERIVATIVES; SURFACES; MONOMERS;
D O I：
10.1002/app.29293
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
A new glycomonomer, 3-acrylamido-3-deoxy-1,2:5,6-di-O-isopropylidene-alpha-D-glucofuranose, was synthesized from D-glucose. This monomer was homo-polymerized and copolymerized with N-isopropylacrylamide in different compositions by free-radical polymerization. The composition of the copolymer was determined with (1)H-NMR spectroscopy. On acid hydrolysis, water-soluble deprotected copolymers were obtained. The protected and deprotected copolymers showed a sharp cloud-point temperature. A linear correlation was obtained between the lower critical solution temperatures and the concentration of glycomonomer in the copolymers (C) 2008 Wiley Periodicals, Inc. J Appl Polym Sci 111: 2607-2615, 2009
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收藏
页码：2607 / 2615
页数：9
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