Gastrointestinal Surgery for Obesity and Diabetes: Weight Loss and Control of Hyperglycemia

被引：28

作者：

Heneghan, H. M. ^{[1
]}

Nissen, S. ^{[2
]}

Schauer, P. R. ^{[1
]}

机构：

[1] Cleveland Clin, Bariatr & Metab Inst, Cleveland, OH 44195 USA

[2] Cleveland Clin, Inst Heart & Vasc, Cleveland, OH 44195 USA

来源：

CURRENT ATHEROSCLEROSIS REPORTS | 2012年 / 14卷 / 06期

关键词：

Obesity; Diabetes mellitus; Bariatric surgery; Metabolic surgery; Diabetes remission; Weight loss; ROUX-EN-Y; LAPAROSCOPIC GASTRIC BYPASS; LONG-TERM MORTALITY; BARIATRIC SURGERY; MORBIDLY OBESE; BILIOPANCREATIC DIVERSION; MEDICAL THERAPY; US ADULTS; RISK; OUTCOMES;

D O I：

10.1007/s11883-012-0285-5

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Obesity is associated with a variety of weight-related metabolic comorbidities. Bariatric surgery (metabolic/gastrointestinal surgery) not only achieves significant and sustainable weight loss, but also induces extraordinary effects on nearly all obesity-related comorbidities, particularly remission of type 2 diabetes mellitus (T2DM). The mechanisms underlying such effects are slowly being elucidated, and it appears that the metabolic benefits of bariatric surgery are not only attributable to weight loss, but there are also weight independent mechanisms at play. This article outlines the metabolic effects of the most commonly performed bariatric procedures, with a particular emphasis on how they affect glucose metabolism and T2DM.

引用

页码：579 / 587

页数：9

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