Zoosporicidal metabolites from an endophytic fungus Cryptosporiopsis sp of Zanthoxylum leprieurii

被引：46

作者：

Talontsi, Ferdinand Mouafo ^{[1
]}

Facey, Petrea ^{[1
]}

Tatong, Michel D. Kongue ^{[1
]}

Islam, M. Tofazzal ^{[2
]}

Frauendorf, Holm ^{[1
]}

Draeger, Siegfried ^{[3
]}

von Tiedemann, Andreas ^{[2
]}

Laatsch, Hartmut ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

[2] Univ Gottingen, Div Plant Pathol & Crop Protect, D-37077 Gottingen, Germany

[3] Tech Univ Carolo Wilhelmina Braunschweig, Inst Microbiol, D-38106 Braunschweig, Germany

来源：

PHYTOCHEMISTRY | 2012年 / 83卷

关键词：

Zanthoxylum leprieurii; Endophytes; Cryptosporiopsis sp; Natural products; Antifungal activity; Zoosporicide; Cytotoxicity; APHANOMYCES-COCHLIOIDES; PLASMOPARA-VITICOLA; PHYTOPHTHORA; OOMYCETE; MOTILITY; ACIDS;

D O I：

10.1016/j.phytochem.2012.06.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two polyketides, cryptosporiopsin A (1) and hydroxypropan-2',3'-diol orsellinate (3), and a natural cyclic pentapeptide (4), together with two known compounds were isolated from the culture of Cryptosporiopsis sp., an endophytic fungus from leaves and branches of Zanthoxylum leprieurii (Rutaceae). The structures of these metabolites were elucidated on the basis of their spectroscopic and spectrometric data. Cryptosporiopsin A and the other metabolites exhibited motility inhibitory and lytic activities against zoospores of the grapevine downy mildew pathogen Plasmopara viticola at 10-25 mu g/mL. In addition, the isolated compounds displayed potent inhibitory activity against mycelial growth of two other peronosporomycete phytopathogens, Pythium ultimum, Aphanomyces cochlioides and a basidiomycetous fungus Rhizoctonia solani. Weak cytotoxic activity on brine shrimp larvae was observed. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：87 / 94

页数：8

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