Central nervous system vasculitis in adults: An update

被引:32
作者
Dutra, Livia Almeida [1 ,2 ]
Silva de Souza, Alexandre Wagner [3 ]
Grinberg-Dias, Gabriela [2 ]
Povoas Barsottini, Orlando Graziani [1 ]
Appenzeller, Simone [4 ]
机构
[1] Univ Fed Sao Paulo, Gen Neurol Div, Dept Neurol & Neurosurg, Sao Paulo, Brazil
[2] Hosp Israelita Albert Einstein, Sao Paulo, Brazil
[3] Univ Fed Sao Paulo, Div Rheumatol, Sao Paulo, Brazil
[4] Univ Estadual Campinas, Div Rheumatol, Campinas, SP, Brazil
关键词
CEREBRAL VASOCONSTRICTION SYNDROME; CATASTROPHIC ANTIPHOSPHOLIPID SYNDROME; PRIMARY CNS VASCULITIS; NEURO-BEHCETS DISEASE; BETA-RELATED ANGIITIS; LYMPHOMATOID GRANULOMATOSIS; CLINICAL VARIANTS; NEUROLOGICAL INVOLVEMENT; SJOGRENS-SYNDROME; SUSAC SYNDROME;
D O I
10.1016/j.autrev.2016.12.001
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Primary central nervous system vasculitis (PCNSV) is a challenging diagnosis due to broad clinical manifestations and variable specificity and sensitivity of laboratory and imaging diagnostic tools. Differential diagnosis includes reversible cerebral vasoconstriction syndrome (RCVS), secondary vasculitis of the CNS and other noninflammatory vasculopathies. Brain biopsy is essential for definitive diagnosis and to exclude mimickers. Recent data show that data large-vessel PCNSV present worse prognosis when compared to small-vessel PCNSV. Herein we review diagnosis and management of PCNSV, secondary vasculitis of CNS and RCVS. (C) 2016 Published by Elsevier B.V.
引用
收藏
页码:123 / 131
页数:9
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