Studies on fentanyl and related compounds IV. Chromatographic and spectrometric discrimination of fentanyl and its derivatives

被引:55
作者
Ohta, H
Suzuki, S
Ogasawara, K
机构
[1] Natl Res Inst Police Sci, Kashiwa, Chiba 2770882, Japan
[2] Tohoku Univ, Inst Pharmaceut, Sendai, Miyagi 9808578, Japan
关键词
D O I
10.1093/jat/23.4.280
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Chromatographic and spectrometric discrimination of fentanyl and its 24 analogues are discussed. Twenty-three of 25 samples were discriminated from each other by gas chromatography (GC), and the combination of GC and mass spectrometry enabled discrimination of all 25 samples. Condensed-phase infrared spectrometry was also useful for the differentiation of structurally similar compounds, but vapor-phase infrared spectra were not useful for discrimination of fentanyls.
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收藏
页码:280 / 285
页数:6
相关论文
共 8 条
[1]   NEW VARIETY OF STREET DRUGS POSES GROWING PROBLEM [J].
BAUM, RM .
CHEMICAL & ENGINEERING NEWS, 1985, 63 (36) :7-16
[2]  
COOPER D, 1986, J FORENSIC SCI, V31, P511
[3]  
HEAGY JA, 1982, MICROGRAM, V15, P181
[4]   STRUCTURE OF BOGUS CHINA WHITE SOLVED [J].
STINSON, S .
CHEMICAL & ENGINEERING NEWS, 1981, 59 (03) :71-72
[5]  
SUZUKI S, 1986, CHEM PHARM BULL, V34, P1340
[7]  
SUZUKI S, 1987, FORENSIC TOXICOL NEW, V5, P5
[8]   SYNTHETIC ANALGESICS - SYNTHESIS AND PHARMACOLOGY OF DIASTEREOISOMERS OF N-[3-METHYL-1-(2-PHENYLETHYL)-4-PIPERIDYL]-N-PHENYLPROPANAMIDE AND N-[3-METHYL-1-(1-METHYL-2-PHENYLETHYL)-4-PIPERIDYL]-N-PHENYLPROPANAMIDE [J].
VANBEVER, WF ;
NIEMEGEERS, CJ ;
JANSSEN, PAJ .
JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (10) :1047-1051