Dietary n-3 PUFA content as a modulator of the femur properties in growing pigs

被引:3
作者
Sobol, Monika [1 ]
Skiba, Grzegorz [1 ]
Raj, Stanislawa [1 ]
机构
[1] Polish Acad Sci, Kielanowski Inst Anim Physiol & Nutr, Dept Anim Nutr, Inst 3 St, PL-05110 Jablonna, Poland
关键词
Bone mineralisation; Fatty acids; Femur; Pigs; X-ray absorptiometry; BONE-MINERAL DENSITY; POLYUNSATURATED FATTY-ACIDS; LONG-TERM SUPPLEMENTATION; MECHANICAL-PROPERTIES; PROSTAGLANDIN E-2; LINOLENIC ACID; ANIMAL-MODELS; FISH-OIL; METABOLISM; MASS;
D O I
10.1017/S0007114518003641
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The relationships between both dietary and empty body fatty acid composition and the morphometry, densitometry, geometry and biomechanical properties of the femur of growing pigs were analysed. A total of thirty-two pigs aged 115 d were divided into four groups (n 8 per group). The pigs were fed either a control diet (group C) or a diet supplemented with linseed oil (rich in alpha-linolenic acid (C18 : 3n-3), group L), fish oil (rich in EPA (C20 : 5n-3) and DHA (C22 : 6n-3), group F) and beef tallow (rich in SFA, group T). The diets differed in n-3 PUFA contents (0 center dot 63-18 center dot 52 g/kg) and n-6:n-3 PUFA ratios (0 center dot 91-14 center dot 51). At 165 d of age, the pigs were slaughtered and the fatty acids in the empty body were determined. Moreover, the left femur was dissected. The cortical wall thickness, cross-sectional area, cortical index, bone mineral content, bone mineral density, maximum elastic strength and maximum strength were lower (P<0 center dot 05) in the femurs of pigs from groups C and T than in those from groups F and L. Significant positive correlations were found between the densitometry, geometry and biomechanical properties of the femur and both dietary and empty body n-3 PUFA content, whereas significant negative correlations were observed between the same properties and both dietary and empty body n-6:n-3 PUFA ratio. The results of the present study suggest that in growing pigs alpha-linolenic acid has a similar positive effect on bone health to that of EPA and DHA.
引用
收藏
页码:508 / 518
页数:11
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