Spectroscopic behavior of metal-drug complexes.: Infrared spectra of Cu(II) dimer complexes with acetazolamide (H2acm) and an analogue sulfonamide (B-H2ats)

被引：21

作者：

Chufán, EE

Pedregosa, JC ^{[1
]}

Ferrer, S

Borrás, J

机构：

[1] Univ Nacl San Luis, Fac Quim Bioquim & Farm, PICT 0230, PID 4929 CONICET, RA-5700 San Luis, Argentina

[2] Univ Valencia, Fac Farm, E-46010 Valencia, Spain

来源：

VIBRATIONAL SPECTROSCOPY | 1999年 / 20卷 / 01期

关键词：

infrared spectrometry; Raman spectrometry; copper(II)); sulfonamides complexes vibrations; 5-acetamido-1,3,4-thiadiazole-2-sulfonamide; 5-tert-butyloxycarbonylamido-1,3,4-thiadiazole-2-sulfonamide;

D O I：

10.1016/S0924-2031(99)00012-0

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The infrared spectra of the drugs H(2)acm and B-H(2)ats, and their copper(II) dimer complexes with stoichiometries [Cu(acm)(NH3)(2)(OH2)](2). H2O and [Cu(B-ats)(NH3)(2)](2) are reported and discussed. The Raman spectra of H(2)acm and B-H(2)ats are also reported. An assignment of H(2)acm and B-H(2)ats modes in the complexes is proposed in comparison with the modes of the free ligands. The spectral modifications due to the deprotonation and coordination effects are analyzed. The nu(N-H) modes of the sulfonamido, carbonamido and N-ring-H of the imine tautomer have been accurately assigned. Important information about the S-O and S-N vibrations has been obtained. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：35 / 45

页数：11

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