What do we know about the diagnostics, treatment and epidemiology of Clostridioides (Clostridium) difficile infection in Europe?

被引：36
作者：
Nagy, Elisabeth [1 ]
机构：
[1] Univ Szeged, Inst Clin Microbiol, Semmelweis U-6, H-6725 Szeged, Hungary
来源：
JOURNAL OF INFECTION AND CHEMOTHERAPY | 2018年 / 24卷 / 03期
关键词：
Clostridioides difficile; Pathogenesis; Epidemiology; Diagnostics; Therapy; European perspective; FECAL MICROBIOTA TRANSPLANTATION; CLINICAL MICROBIOLOGY; CHANGING EPIDEMIOLOGY; GUIDANCE DOCUMENT; TOXIN-B; DIARRHEA; RECURRENT; SOCIETY; UPDATE; VIRULENCE;
D O I：
10.1016/j.jiac.2017.12.003
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Clostridium difficile, recently reclassified as Clostridioides difficile is responsible for a significant part of diarrheal diseases in the hospitals and in the community. Besides the main pathogenic factors, toxin A, toxin B and the binary toxin, several other putative virulence factors have been investigated. This manuscript summarize recent findings in Europe concerning source of infection, epidemiology of CDI, the changing pattern of PCR ribotypes of C. difficile strains in different European countries, recommendations for diagnosis and treatment of CDI. (c) 2017 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：164 / 170
页数：7
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