Carcinoma in situ -from clinical observation to a paradigm shift for testicular carcinogenesis

被引：2
作者：
Toppari, Jorma [1 ,2 ,3 ]
机构：
[1] Univ Turku, Dept Physiol, FI-20520 Turku, Finland
[2] Univ Turku, Dept Paediat, FI-20520 Turku, Finland
[3] Rigshosp, Dept Growth & Reprod, DK-2100 Copenhagen, Denmark
来源：
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY | 2013年 / 57卷 / 2-4期
基金：
芬兰科学院;
关键词：
testis; cancer; fertility; CIS; germ cell; GERM-CELL TUMORS; TESTIS; CHILDREN; INSITU;
D O I：
10.1387/ijdb.130145jt
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Carcinoma in situ in the testis has its origin in the fetal gonad and leads to testicular cancer in young adulthood. It can be detected in a testicular biopsy and treated with irradiation, which can preserve testosterone production of the man. These are the key findings of Niels E. Skakkebaek that changed our view of testicular tumourigenesis during the last fifty years. These and other findings are discussed in this interview-based review of testicular germ cell cancer.
引用
收藏
页码：221 / 223
页数：3
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