A low-cost thin layer coulometric microfluidic device based on an ion-selective membrane for calcium determination

被引：20

作者：

Dorokhin, Denis ^{[1
]}

Crespo, Gaston A. ^{[1
]}

Afshar, Majid Ghahraman ^{[1
]}

Bakker, Eric ^{[1
]}

机构：

[1] Univ Geneva, Dept Inorgan & Analyt Chem, CH-1211 Geneva, Switzerland

来源：

ANALYST | 2014年 / 139卷 / 01期

基金：

瑞士国家科学基金会;

关键词：

D O I：

10.1039/c3an01715j

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A prototype of a low-cost and easy-to-use thin layer coulometric microfluidic device based on an ion-selective membrane for calcium detection is described. The microfluidic device was fabricated and consequently assembled with inexpensive materials without using sophisticated and centralized fabrication laboratory facilities. The linear range of the device is found to be 10-100 mu M for a 60 s current integration time. Preliminary validations showed that the microfluidic device is suitable for the quantification of calcium in mineral water.

引用

页码：48 / 51

页数：4

共 18 条

[1]

Chin CurtisD., 2013, Point-of-Care Diagnostics on a Chip, P3

[2] Fabrication of the array chlorine ion sensor based on microfluidic device framework [J].

Chou, Jung-Chuan ;

Ye, Guan-Chen ;

Wu, Da-Gong ;

Chen, Chien-Cheng .

SOLID-STATE ELECTRONICS, 2012, 77 :87-92

[3] Integrated microfluidic devices [J].

Erickson, D ;

Li, DQ .

ANALYTICA CHIMICA ACTA, 2004, 507 (01) :11-26

[4] Interference Compensation for Thin Layer Coulometric Ion-Selective Membrane Electrodes by the Double Pulse Technique [J].

Grygolowicz-Pawlak, Ewa ;

Numnuam, Apon ;

Thavarungkul, Panote ;

Kanatharana, Proespichaya ;

Bakker, Eric .

ANALYTICAL CHEMISTRY, 2012, 84 (03) :1327-1335

[5] Background current elimination in thin layer ion-selective membrane coulometry [J].

Grygolowicz-Pawlak, Ewa ;

Bakker, Eric .

ELECTROCHEMISTRY COMMUNICATIONS, 2010, 12 (09) :1195-1198

[6] Thin Layer Coulometry with Ionophore Based Ion-Selective Membranes [J].

Grygolowicz-Pawlak, Ewa ;

Bakker, Eric .

ANALYTICAL CHEMISTRY, 2010, 82 (11) :4537-4542

[7] Microfluidic platforms for lab-on-a-chip applications [J].

Haeberle, Stefan ;

Zengerle, Roland .

LAB ON A CHIP, 2007, 7 (09) :1094-1110

[8] Microfabrication techniques for chemical/biosensors [J].

Hierlemann, A ;

Brand, O ;

Hagleitner, C ;

Baltes, H .

PROCEEDINGS OF THE IEEE, 2003, 91 (06) :839-863

[9] Microfluidic ion-sensing devices [J].

Johnson, R. Daniel ;

Gaualas, Vasilis G. ;

Daunert, Sylvia ;

Bachas, Leonidas G. .

ANALYTICA CHIMICA ACTA, 2008, 613 (01) :20-30

[10] Micro Total Analysis Systems: Fundamental Advances and Applications in the Laboratory, Clinic, and Field [J].

Kovarik, Michelle L. ;

Ornoff, Douglas M. ;

Melvin, Adam T. ;

Dobes, Nicholas C. ;

Wang, Yuli ;

Dickinson, Alexandra J. ;

Gach, Philip C. ;

Shah, Pavak K. ;

Allbritton, Nancy L. .

ANALYTICAL CHEMISTRY, 2013, 85 (02) :451-472

← 1 2 →