Supercritical fluid chromatography for the 21st century

被引：229

作者：

Taylor, Larry T. ^{[1
]}

机构：

[1] Virginia Tech, Dept Chem, Blacksburg, VA 24061 USA

来源：

JOURNAL OF SUPERCRITICAL FLUIDS | 2009年 / 47卷 / 03期

关键词：

Supercritical fluid chromatography; Packed columns; Capillary columns; Mass spectrometry; Preparative scale separations; Simulated moving bed; Chiral separations; PREPARATIVE CHIRAL CHROMATOGRAPHY; PRESSURE GAS CHROMATOGRAPHY; SIMULATED MOVING-BED; MASS-SPECTROMETRY; STATIONARY PHASES; DRUG DISCOVERY; SFC; SEPARATION; PURIFICATION; ENANTIOMERS;

D O I：

10.1016/j.supflu.2008.09.012

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A brief historical review of supercritical fluid chromatography (SFC) as it pertains to open tubular (i.e. capillary) column SFC and packed column SFC is presented. Specific sections include (1) early emphasis on open tubular columns and non-polar analytes; (2) packed column SFC for separation of more polar analytes; (3) preparative scale packed column SFC. The review is completed by discussing current trends in SFC such as (a) chiral separations, (b) achiral separations, (c) simulated moving bed SFC, and (d) SFC coupled to mass spectrometry. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：566 / 573

页数：8

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