3-Component palladium-indium mediated diastereoselective cascade allylation of imines with allenes and aryl iodides

被引：72

作者：

Cooper, IR ^{[1
]}

Grigg, R

MacLachlan, WS

Thornton-Pett, M

Sridharan, V

机构：

[1] Univ Leeds, Sch Chem, Mol Innovat Divers & Automated Synth Ctr, Leeds LS2 9JT, W Yorkshire, England

[2] GlaxoSmithkline, Harlow CM19 5AW, Essex, England

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 13期

关键词：

D O I：

10.1039/b202940e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new palladium-indium diastereoselective cascade allylation of imines using allenes and aryl iodides is described; N-tosyl and N-aryl homoallyl amines were obtained in moderate to good yields and excellent diastereoselectivity was observed when enantiomerically pure N-tert-butane-sulfinyl imines were employed in the cascade.

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页码：1372 / 1373

页数：2

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