Endogenous production of nitric oxide synthase inhibitors

被引:43
|
作者
Anthony, S [1 ]
Leiper, J [1 ]
Vallance, P [1 ]
机构
[1] UCL, Ctr Clin Pharmacol, BHF Labs, London, England
关键词
asymmetric methylarginine; dimethylarginine dimethylaminohydrolase; nitric oxide synthase; protein-arginine methyltransferase;
D O I
10.1191/1358863x05vm595oa
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Numerous reports have indicated that the plasma concentration of endogenously produced inhibitors of nitric oxide synthase are elevated in human disease states. In this review we discuss recent advances in our understanding of the enzymes responsible for the synthesis of these inhibitors.
引用
收藏
页码:S3 / S9
页数:7
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