Perils of the Pathologic Complete Response

被引:42
作者
Rose, Brent S. [1 ]
Winer, Eric P. [2 ]
Mamon, Harvey J. [2 ,3 ]
机构
[1] Harvard Radiat Oncol Program, Boston, MA 02115 USA
[2] Dana Farber Canc Inst, Boston, MA 02115 USA
[3] Brigham & Womens Hosp, 75 Francis St, Boston, MA 02115 USA
关键词
OPERABLE BREAST-CANCER; DOSE-INTENSIFIED CHEMOTHERAPY; SURGICAL ADJUVANT BREAST; ADVANCED RECTAL-CANCER; NEOADJUVANT CHEMOTHERAPY; PREOPERATIVE CHEMOTHERAPY; DARBEPOETIN ALPHA; ANTICANCER DRUGS; RANDOMIZED-TRIAL; PREPARE TRIAL;
D O I
10.1200/JCO.2016.68.1718
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:3959 / U40
页数:5
相关论文
共 43 条
[1]  
[Anonymous], BIOSTATISTICS
[2]   Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial [J].
Baselga, Jose ;
Bradbury, Ian ;
Eidtmann, Holger ;
Di Cosimo, Serena ;
de Azambuja, Evandro ;
Aura, Claudia ;
Gomez, Henry ;
Dinh, Phuong ;
Fauria, Karine ;
Van Dooren, Veerle ;
Aktan, Gursel ;
Goldhirsch, Aron ;
Chang, Tsai-Wang ;
Horvath, Zsolt ;
Coccia-Portugal, Maria ;
Domont, Julien ;
Tseng, Ling-Min ;
Kunz, Georg ;
Sohn, Joo Hyuk ;
Semiglazov, Vladimir ;
Lerzo, Guillermo ;
Palacova, Marketa ;
Probachai, Volodymyr ;
Pusztai, Lajos ;
Untch, Michael ;
Gelber, Richard D. ;
Piccart-Gebhart, Martine .
LANCET, 2012, 379 (9816) :633-640
[3]   Sequential preoperative or postoperative docetaxel added to preoperative doxorubicin plus cyclophosphamide for operable breast cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-27 [J].
Bear, HD ;
Anderson, S ;
Smith, RE ;
Geyer, CE ;
Mamounas, EP ;
Fisher, B ;
Brown, AM ;
Robidoux, A ;
Margolese, R ;
Kahlenberg, MS ;
Paik, S ;
Soran, A ;
Wickerham, DL ;
Wolmark, N .
JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (13) :2019-2027
[4]   Pathologic Complete Response As a Potential Surrogate for the Clinical Outcome in Patients With Breast Cancer After Neoadjuvant Therapy: A Meta-Regression of 29 Randomized Prospective Studies [J].
Berruti, Alfredo ;
Amoroso, Vito ;
Gallo, Fabio ;
Bertaglia, Valentina ;
Simoncini, Edda ;
Pedersini, Rebecca ;
Ferrari, Laura ;
Bottini, Alberto ;
Bruzzi, Paolo ;
Sormani, Maria Pia .
JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (34) :3883-U288
[5]   Neoadjuvant Therapy in Breast Cancer as a Basis for Drug Approval [J].
Berry, Donald A. ;
Hudis, Clifford A. .
JAMA ONCOLOGY, 2015, 1 (07) :875-876
[6]   What is the clinical benefit of preoperative chemoradiotherapy with 5FU/leucovorin for T3-4 rectal cancer in a pooled analysis of EORTC 22921 and FFCD 9203 trials: Surrogacy in question? [J].
Bonnetain, F. ;
Bosset, J. F. ;
Gerard, J. P. ;
Calais, G. ;
Conroy, T. ;
Mineur, L. ;
Bouche, O. ;
Maingon, P. ;
Chapet, O. ;
Radosevic-Jelic, L. ;
Methy, N. ;
Collette, L. .
EUROPEAN JOURNAL OF CANCER, 2012, 48 (12) :1781-1790
[7]   Neoadjuvant therapy with paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide chemotherapy and concurrent trastuzumab in human epidermal growth factor receptor 2-positive operable breast cancer: An update of the initial randomized study population and data of additional patients treated with the same regimen [J].
Buzdar, Aman U. ;
Valero, Vicente ;
Ibrahim, Nuhad K. ;
Francis, Deborah ;
Broglio, Kristine R. ;
Theriault, Richard L. ;
Pusztai, Lajos ;
Green, Marjorie C. ;
Singletary, Sonja E. ;
Hunt, Kelly K. ;
Sahin, Aysegul A. ;
Esteva, Francisco ;
Symmans, William F. ;
Ewer, Michael S. ;
Buchholz, Thomas A. ;
Hortobagyi, Gabriel N. .
CLINICAL CANCER RESEARCH, 2007, 13 (01) :228-233
[8]   Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: Results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer [J].
Buzdar, AU ;
Ibrahim, NK ;
Francis, D ;
Booser, DJ ;
Thomas, ES ;
Theriault, RL ;
Pusztai, L ;
Green, MC ;
Arun, BK ;
Giordano, SH ;
Cristofanilli, M ;
Frye, DK ;
Smith, TL ;
Hunt, KK ;
Singletary, SE ;
Sahin, AA ;
Ewer, MS ;
Buchholz, TA ;
Berry, D ;
Hortobagyi, GN .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) :3676-3685
[9]   Molecular Origins of Cancer Molecular Basis of Metastasis [J].
Chiang, Anne C. ;
Massague, Joan .
NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (26) :2814-2823
[10]   Primary chemotherapy in operable breast carcinoma comparing CMF (cyclophosphamide, methotrexate, 5-fluorouracil) with an anthracycline-containing regimen: short-term responses translated into long-term outcomes [J].
Cocconi, G ;
Di Blasio, B ;
Boni, C ;
Bisagni, G ;
Rondini, E ;
Bella, MA ;
Leonardi, F ;
Savoldi, L ;
Vallisneri, C ;
Camisa, R ;
Bruzzi, P .
ANNALS OF ONCOLOGY, 2005, 16 (09) :1469-1476