Is preoperative ultrasound tumor size a prognostic factor in endometrial carcinoma patients?

被引：5

作者：

Ambrosio, Marco ^{[1
]}

Raffone, Antonio ^{[2
,3
]}

Alletto, Andrea ^{[3
]}

Cini, Chiara ^{[3
]}

Filipponi, Francesco ^{[3
]}

Neola, Daniele ^{[4
]}

Fabbri, Matilde ^{[3
]}

Arena, Alessandro ^{[2
,3
]}

Raimondo, Diego ^{[2
]}

Salucci, Paolo ^{[3
]}

Guerrini, Manuela ^{[2
]}

Travaglino, Antonio ^{[5
]}

Paradisi, Roberto ^{[3
]}

Mollo, Antonio ^{[6
]}

Seracchioli, Renato ^{[2
,3
]}

Casadio, Paolo ^{[2
]}

机构：

[1] Osped Maggiore Bologna, Azienda Unita Sanitaria Locale Bologna, Mother Child Dept, Bologna, Italy

[2] IRCCS Azienda Osped Univ Bologna, Div Gynaecol & Human Reprod Physiopathol, Bologna, Italy

[3] Univ Bologna, Dept Med & Surg Sci, Bologna, Italy

[4] Univ Naples Federico II, Sch Med, Dept Neurosci Reprod Sci & Dent, Gynecol & Obstet Unit, Naples, Italy

[5] Agostino Gemelli Univ Polyclin, Dept Womans Hlth Sci, Gynecopathol & Breast Pathol Unit, Rome, Italy

[6] Univ Salerno, Dept Med Surg & Dent, Schola Med Salernitana, Gynecol & Obstet Unit, Baronissi, Italy

来源：

FRONTIERS IN ONCOLOGY | 2022年 / 12卷

关键词：

risk assessment; cancer; tumor; prognosis; death; recurrence; relapse; MYOMETRIAL INVASION; PRECISION MEDICINE; CANCER; LYMPHADENECTOMY; GUIDELINES; PREDICTOR; DIAMETER; DEPTH; GRADE;

D O I：

10.3389/fonc.2022.993629

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

ObjectiveWe aimed to assess the prognostic value of preoperative ultrasound tumor size in EC through a single center, observational, retrospective, cohort study. MethodsMedical records and electronic clinical databases were searched for all consecutive patients with EC, preoperative ultrasound scans available to ad hoc estimate tumor size, and a follow-up of at least 2-year, at our Institution from January 2010 to June 2018. Patients were divided into two groups based on different dimensional cut-offs for the maximum tumor diameter: 2, 3 and 4 cm. Differences in overall survival (OS), disease specific survival (DSS) and progression-free survival (PFS) were assessed among the groups by using the Kaplan-Meier estimator and the log-rank test. Results108 patients were included in the study. OS, DSS and PFS did not significantly differ between the groups based on the different tumor diameter cut-offs. No significant differences were found among the groups sub-stratified by age, BMI, FIGO stage, FIGO grade, lymphovascular space invasion status, myometrial invasion, lymph nodal involvement, histotype, and adjuvant treatment. ConclusionsPreoperative ultrasound tumor size does not appear as a prognostic factor in EC women.

引用

页数：9

共 37 条

[21] Histopathological characterization of ProMisE molecular groups of endometrial cancer [J].