Chip in a lab: Microfluidics for next generation life science research

被引:127
作者
Streets, Aaron M. [1 ,2 ]
Huang, Yanyi [1 ,2 ,3 ]
机构
[1] Peking Univ, Biodynam Opt Imaging Ctr BIOPIC, Beijing 100871, Peoples R China
[2] Peking Univ, Coll Engn, Beijing 100871, Peoples R China
[3] Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China
基金
中国国家自然科学基金;
关键词
biomedical equipment; bioMEMS; lab-on-a-chip; microchannel flow; patient diagnosis; SINGLE-CELL ANALYSIS; ABSOLUTE QUANTITATION; REAL-TIME; BACTERIA; SYSTEM; GENOME; GROWTH; EXPRESSION; MICROBES; PROTEINS;
D O I
10.1063/1.4789751
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Microfluidic circuits are characterized by fluidic channels and chambers with a linear dimension on the order of tens to hundreds of micrometers. Components of this size enable lab-on-a-chip technology that has much promise, for example, in the development of point-of-care diagnostics. Micro-scale fluidic circuits also yield practical, physical, and technological advantages for studying biological systems, enhancing the ability of researchers to make more precise quantitative measurements. Microfluidic technology has thus become a powerful tool in the life science research laboratory over the past decade. Here we focus on chip-in-a-lab applications of microfluidics and survey some examples of how small fluidic components have provided researchers with new tools for life science research. (C) 2013 American Institute of Physics. [http://dx.doi.org/10.1063/1.4789751]
引用
收藏
页数:23
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