COVID-19 Precipitating Status Epilepticus in a Pediatric Patient

被引:16
作者
Farley, Madison [1 ]
Zuberi, Jamshed [2 ]
机构
[1] St Georges Univ, Sch Med, True Blue, Grenada
[2] St Josephs Univ, Med Ctr, Dept Surg, Paterson, NJ USA
关键词
COVID-19; Pediatrics; SARS Virus; Status Epilepticus;
D O I
10.12659/AJCR.925776
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Patient: Male, 8-year-old Final Diagnosis: COVID-19 Symptoms: Abdominal pain center dot respiratory distress center dot status epilepticus center dot vomiting Medication: - Clinical Procedure: - Specialty: Infectious Diseases center dot Pediatrics and Neonatology Objective: Unusual clinical course Background: As the severe acute respiratory syndrome coronavirus 2 (SARS CoV2) spreads around the world infecting people of all ages, clinicians and researchers are working to gather data on the presentation of coronavirus disease (COVID-19). Further study is necessary to better diagnose and treat COVID-19 patients. Case Report: We describe the case of an 8-year-old boy admitted with status epilepticus, who also tested positive for COVID-19, while afebrile, with no initial respiratory symptoms. Benzodiazepines were given per treatment guidelines, abating the seizure activity. He subsequently developed respiratory distress and desaturation requiring temporary emergent intubation. All clinical symptoms resolved within a few hours. Results of a computed tomography (CT) scan of the brain were within normal limits. Results of a 24-h electroencephalogram (EEG) were abnormal, indicative of diffuse cerebral dysfunction. As a result of intubation and findings of bilateral infiltrates on chest x-ray, a COVID-19 test was administered and the result was positive. Conclusions: For proper diagnosis and treatment, patients and clinicians should be aware that COVID-19 may not present in the typical fashion of respiratory distress and fever. The present case suggests a rare neurological presentation of COVID-19.
引用
收藏
页码:e925776 / 1
页数:4
相关论文
共 11 条
[1]   Severe neurologic syndrome associated with Middle East respiratory syndrome corona virus (MERS-CoV) [J].
Arabi, Y. M. ;
Harthi, A. ;
Hussein, J. ;
Bouchama, A. ;
Johani, S. ;
Hajeer, A. H. ;
Saeed, B. T. ;
Wahbi, A. ;
Saedy, A. ;
AlDabbagh, T. ;
Okaili, R. ;
Sadat, M. ;
Balkhy, H. .
INFECTION, 2015, 43 (04) :495-501
[2]   Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host-Virus Interaction, and Proposed Neurotropic Mechanisms [J].
Baig, Abdul Mannan ;
Khaleeq, Areeba ;
Ali, Usman ;
Syeda, Hira .
ACS CHEMICAL NEUROSCIENCE, 2020, 11 (07) :995-998
[3]   Coronavirus Disease 2019 in Children - United States, February 12-April 2, 2020 [J].
Bialek, Stephanie ;
Gierke, Ryan ;
Hughes, Michelle ;
McNamara, Lucy A. ;
Pilishvili, Tamara ;
Skoff, Tami .
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2020, 69 (14) :422-426
[4]   Relationship between five common viruses and febrile seizure in children [J].
Chung, Brian ;
Wong, Virginia .
ARCHIVES OF DISEASE IN CHILDHOOD, 2007, 92 (07) :589-593
[5]   Epidemiology of COVID-19 Among Children in China [J].
Dong, Yuanyuan ;
Mo, Xi ;
Hu, Yabin ;
Qi, Xin ;
Jiang, Fan ;
Jiang, Zhongyi ;
Tong, Shilu .
PEDIATRICS, 2020, 145 (06)
[6]   Clinical Characteristics of Coronavirus Disease 2019 in China [J].
Guan, W. ;
Ni, Z. ;
Hu, Yu ;
Liang, W. ;
Ou, C. ;
He, J. ;
Liu, L. ;
Shan, H. ;
Lei, C. ;
Hui, D. S. C. ;
Du, B. ;
Li, L. ;
Zeng, G. ;
Yuen, K. -Y. ;
Chen, R. ;
Tang, C. ;
Wang, T. ;
Chen, P. ;
Xiang, J. ;
Li, S. ;
Wang, Jin-lin ;
Liang, Z. ;
Peng, Y. ;
Wei, L. ;
Liu, Y. ;
Hu, Ya-hua ;
Peng, P. ;
Wang, Jian-ming ;
Liu, J. ;
Chen, Z. ;
Li, G. ;
Zheng, Z. ;
Qiu, S. ;
Luo, J. ;
Ye, C. ;
Zhu, S. ;
Zhong, N. .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (18) :1708-1720
[7]   The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients [J].
Li, Yan-Chao ;
Bai, Wan-Zhu ;
Hashikawa, Tsutomu .
JOURNAL OF MEDICAL VIROLOGY, 2020, 92 (06) :552-555
[8]   Neutrophil-to-lymphocyte ratio as an independent risk factor for mortality in hospitalized patients with COVID-19 [J].
Liu, Yuwei ;
Du, Xuebei ;
Chen, Jing ;
Jin, Yalei ;
Peng, Li ;
Wang, Harry H. X. ;
Luo, Mingqi ;
Chen, Ling ;
Zhao, Yan .
JOURNAL OF INFECTION, 2020, 81 (01) :E6-E12
[9]   Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China [J].
Mao, Ling ;
Jin, Huijuan ;
Wang, Mengdie ;
Hu, Yu ;
Chen, Shengcai ;
He, Quanwei ;
Chang, Jiang ;
Hong, Candong ;
Zhou, Yifan ;
Wang, David ;
Miao, Xiaoping ;
Li, Yanan ;
Hu, Bo .
JAMA NEUROLOGY, 2020, 77 (06) :683-690
[10]   Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China [J].
Qin, Chuan ;
Zhou, Luoqi ;
Hu, Ziwei ;
Zhang, Shuoqi ;
Yang, Sheng ;
Tao, Yu ;
Xie, Cuihong ;
Ma, Ke ;
Shang, Ke ;
Wang, Wei ;
Tian, Dai-Shi .
CLINICAL INFECTIOUS DISEASES, 2020, 71 (15) :762-768