Cardiac amyloidosis: How to recognize them and manage them?

被引:5
作者
Bodez, Diane [1 ,2 ,3 ,4 ]
Galat, Arnault [1 ,2 ,3 ,4 ]
Guellich, Aziz [1 ,2 ,3 ,4 ]
Deux, Jean-Francois [2 ,3 ,5 ]
Rosso, Jean [2 ,6 ]
Le Bras, Fabien [2 ,3 ,7 ]
Funalot, Benoit [3 ,8 ,9 ]
Fanen, Pascale [3 ,8 ,9 ]
Benhaiem, Nicole [2 ,8 ,9 ]
Plante-Bordeneuve, Violaine [2 ,3 ,4 ,10 ]
Dubois-Rande, Jean-Luc [1 ,3 ,4 ]
Lellouche, Nicolas [1 ,2 ,3 ,4 ]
Guendouz, Soulef [1 ,2 ,3 ,4 ]
Molinier-Frenkel, Valerie [1 ,3 ,11 ]
Mohty, Dania [12 ]
Damy, Thibaud [1 ,2 ,3 ,4 ]
机构
[1] CHU Henri Mondor, Serv Cardiol, F-94010 Creteil, France
[2] CHU Henri Mondor, Reseau Amylose Mondor, F-94010 Creteil, France
[3] Univ Paris Est Creteil, Fac Med, F-94010 Creteil, France
[4] CHU Henri Mondor, GRC ARI, DHU ATVB, Inserm,U955,IMRB, F-94010 Creteil, France
[5] CHU Henri Mondor, Serv Imagerie Med, F-94010 Creteil, France
[6] CHU Henri Mondor, Serv Med Nucl, F-94010 Creteil, France
[7] CHU Henri Mondor, Serv Hematol, F-94010 Creteil, France
[8] CHU Henri Mondor, Dept Genet, F-94010 Creteil, France
[9] CHU Henri Mondor, Serv Anatomopathol, F-94010 Creteil, France
[10] CHU Henri Mondor, Serv Neurol, F-94010 Creteil, France
[11] CHU Henri Mondor, Lab Immunol, F-94010 Creteil, France
[12] CHU Limoges, Hop Dupuytren, Serv Cardiol, F-87042 Limoges, France
来源
PRESSE MEDICALE | 2016年 / 45卷 / 10期
关键词
SYSTEMIC AMYLOIDOSIS; MONOCLONAL GAMMOPATHY; MAGNETIC-RESONANCE; EUROPEAN-SOCIETY; HEREDITARY; DIAGNOSIS; ECHOCARDIOGRAPHY; CARDIOMYOPATHY; PREVALENCE; PHENOTYPE;
D O I
10.1016/j.lpm.2016.07.001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiac amyloidosis must be suspected in all cases of hypertrophic cardiomyopathy with preserved left ventricular ejection fraction to allow specific management. Final diagnosis needs pathological evidence, but bone scintigraphy may be an alternative for TTR amyloidosis. Invasive samplings are limited by new tools. Amyloidosis typing is required to start specific therapies if possible. Main specific treatments that are available are chemotherapy for AL; transthyretin stabilizer or gene therapy, studied for TTR-related cardiac amyloidosis.
引用
收藏
页码:844 / 854
页数:11
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