Koilocytosis: Correlations With High-Risk HPV and Its Comparison on Tissue Sections and Cytology, Urothelial Carcinoma

被引：17
|
作者：
Aggarwal, Seema [1 ,2 ]
Arora, Vinod K. [1 ,2 ]
Gupta, Sanjay [3 ]
Singh, Navjeevan [1 ,2 ]
Bhatia, Arati [1 ,2 ]
机构：
[1] Univ Coll Med Sci, Dept Pathol, Delhi 110095, India
[2] GTB Hosp, Delhi 110095, India
[3] Inst Cytopathol & Prevent Oncol, Dept Cytopathol, Noida, India
来源：
DIAGNOSTIC CYTOPATHOLOGY | 2009年 / 37卷 / 03期
关键词：
urothelial carcinoma; urine cytology; koilocytosis; HPV DNA; TRANSITIONAL-CELL CARCINOMA; HUMAN PAPILLOMAVIRUS INFECTION; POLYMERASE-CHAIN-REACTION; URINARY-BLADDER; BOVINE PAPILLOMAVIRUS; INDIAN WOMEN; CANCER; DNA; OVEREXPRESSION; HYBRIDIZATION;
D O I：
10.1002/dc.20978
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
The aim of this study were (1) To correlate koilocytosis with high risk HPV(HrHPV) DNA in urinary bladder carcinoma and (2) To compare detection of koilocytosis on tissue sections and urine cytology. Biopsy and cytologic specimens from 33 patients of urinary bladder carcinoma were analyzed. HPV DNA was detected by PCR on biopsy specimens using consensus primers MY09 and MY11. Koilocytosis was assessed both on tissue sections and urine cytology. HrHPV DNA was found in 14 of 33 bladder carcinoma. Koilocytosis was seen tissue sections from 13 patients. Eleven of these were HrHPV DNA positive (positive predictive value 84.6%). Koilocytosis was seen in urine cytology in three patients. All three were positive for HrHPV DNA. To conclude koilocytosis is a good morphological marker for HrHPV DNA in the urothelium. Tissue sections are better than cytologic smears for detection of koilocytes. Diagn. Cytopathol, 2009; 37:174-177. (C) 2009 Wiley-Liss, Inc.
引用
收藏
页码：174 / 177
页数：4
相关论文
共 50 条
  • [21] Upper tract urothelial carcinoma: epidemiology, presentation, and high-risk endemic populations
    Clark, Cassra B.
    Matheny, Meghan
    Raman, Jay D.
    CURRENT OPINION IN UROLOGY, 2025, 35 (01) : 53 - 57
  • [22] Evaluation of HPV-16 and HPV-18 Genotyping for the Triage of Women With High-Risk HPV plus Cytology-Negative Results
    Wright, Thomas C., Jr.
    Stoler, Mark H.
    Sharma, Abha
    Zhang, Guili
    Behrens, Catherine
    Wright, Teresa L.
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2011, 136 (04) : 578 - 586
  • [23] Comparison of Abbott RealTime High Risk HPV and Hybrid Capture 2 for the detection of high-risk HPV DNA in a referral population setting
    Venturoli, Simona
    Leo, Elisa
    Nocera, Martina
    Barbieri, Daniela
    Cricca, Monica
    Costa, Silvano
    Santini, Donatella
    Zerbini, Marialuisa
    JOURNAL OF CLINICAL VIROLOGY, 2012, 53 (02) : 121 - 124
  • [24] Comparison of HPV Genotyping Assays and Hybrid Capture 2 for Detection of High-Risk HPV in Cervical Specimens
    Um, Tae Hyun
    Lee, Eun Hee
    Chi, Hyun-Sook
    Kim, Jong-Won
    Hong, Young-Joon
    Cha, Young Joo
    ANNALS OF CLINICAL AND LABORATORY SCIENCE, 2011, 41 (01) : 48 - 55
  • [25] Five and Ten-Year Outcomes of Neoadjuvant Chemotherapy and Surgery for High-Risk Upper Tract Urothelial Carcinoma
    Adibi, Mehrad
    McCormick, Barrett
    Economides, Minas P.
    Petros, Firas
    Xiao, Lianchun
    Guo, Charles
    Shah, Amishi
    Kamat, Ashish M.
    Dinney, Colin
    Navai, Neema
    Gao, Jianjun
    Siefker-Radtke, Arlene
    Matin, Surena F.
    Campbell, Matthew T.
    CLINICAL GENITOURINARY CANCER, 2022, 20 (02) : 176 - 182
  • [26] Comparison of Abbott RealTime High-Risk HPV and Hybrid Capture 2 Assays for Detection of HPV Infection
    Ko, Kiwoong
    Yu, Shinae
    Lee, Eun Hee
    Park, Hyosoon
    Woo, Hee-Yeon
    Kwon, Min-Jung
    ANNALS OF CLINICAL AND LABORATORY SCIENCE, 2016, 46 (05) : 522 - 528
  • [27] Comparison of the Cepheid Xpert HPV test and the HC2 High-Risk HPV DNA Test for detection of high-risk HPV infection in cervical smear samples in SurePath preservative fluid
    Rabaan, Ali A.
    Alfaraj, Shatha A.
    Alkhalifah, Mohammed A.
    JOURNAL OF MEDICAL MICROBIOLOGY, 2018, 67 (05) : 676 - 680
  • [28] Comparison Study of BD Onclarity HPV With digene HC2 High-Risk HPV DNA Test and Roche Cobas 4800 HPV for Detecting High-Risk Human Papillomavirus in Japan
    Nakamura, Mitsuhiro
    Nakade, Kyohei
    Orisaka, Shunsuke
    Iwadare, Junpei
    Mizumoto, Yasunari
    Fujiwara, Hiroshi
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2019, 151 (03) : 263 - 269
  • [29] Oncological Outcomes of Distal Ureterectomy for High-Risk Urothelial Carcinoma: A Multicenter Study by The French Bladder Cancer Committee
    Masson-Lecomte, Alexandra
    Vaillant, Victoire
    Roumiguie, Mathieu
    Levy, Stephan
    Pradere, Benjamin
    Peyromaure, Michael
    Duquesne, Igor
    De la Taille, Alexandre
    Lebacle, Cedric
    Panis, Adrien
    Traxer, Olivier
    Leon, Priscilla
    Hulin, Maud
    Xylinas, Evanguelos
    Audenet, Francois
    Seisen, Thomas
    Loriot, Yohann
    Allory, Yves
    Roupret, Morgan
    Neuzillet, Yann
    CANCERS, 2022, 14 (21)
  • [30] The Impact of High-Risk HPV Genotypes Other Than HPV 16/18 on the Natural Course of Abnormal Cervical Cytology: A Korean HPV Cohort Study
    So, Kyeong A.
    Kim, Mi Jung
    Lee, Ki-Heon
    Lee, In-Ho
    Kim, Mi Kyung
    Lee, Yoo Kyung
    Hwang, Chang-Sun
    Jeong, Mi Seon
    Kee, Mee-Kyung
    Kang, Chun
    Cho, Chi Heum
    Kim, Seok Mo
    Hong, Sung Ran
    Kim, Ki Tae
    Lee, Won-Chul
    Park, Jong Sup
    Kim, Tae Jin
    CANCER RESEARCH AND TREATMENT, 2016, 48 (04): : 1313 - 1320
12345