FeNH4(SO4)2•12H2O (alum)-catalyzed preparation of 1,4-dihydropyridines: improved conditions for the Hantzsch reaction

被引：8

作者：

Mohammadi, Ali A. ^{[1
]}

Hadadzahmatkesh, Armin ^{[1
]}

Asghariganjeh, Mohammad R. ^{[2
]}

机构：

[1] Islamic Azad Univ, Sabzevar Branch, Dept Chem, Sabzevar, Iran

[2] Islamic Azad Univ, Omidieh Branch, Dept Chem, Omidieh, Iran

来源：

MONATSHEFTE FUR CHEMIE | 2012年 / 143卷 / 06期

关键词：

Hantzsch reaction; 1,4-Dihydropyridines; FeNH4(SO4)(2)center dot 12H(2)O; Multi-component reactions; ONE-POT SYNTHESIS; POLYHYDROQUINOLINE DERIVATIVES; 3-COMPONENT REACTION; EFFICIENT; BIGINELLI; CATALYST; PROTOCOL; ACID;

D O I：

10.1007/s00706-011-0672-6

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

FeNH4(SO4)(2)center dot 12H(2)O (alum) efficiently catalyzes the one-pot three-component reaction of dimedone, aldehydes, and 3-aminocrotonate to afford 1,4-dihydropyridines. The work-up is easy, and the products are obtained in good to excellent yields and high purity.

引用

页码：931 / 933

页数：3

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