Cu(II) salen complex with propylene linkage: An efficient catalyst in the formation of C-X bonds (X = N, O, S) and biological investigations

被引：33

作者：

Azam, Mohammad ^{[1
]}

Dwivedi, Sourabh ^{[2
]}

Al-Resayes, Saud I. ^{[1
]}

Adil, S. F. ^{[1
]}

Islam, Mohammad Shahidul ^{[1
]}

Trzesowska-Kruszynska, Agata ^{[3
]}

Kruszynski, Rafal ^{[3
]}

Lee, Dong-Ung ^{[4
]}

机构：

[1] King Saud Univ, Dept Chem, Coll Sci, POB 2455, Riyadh 11451, Saudi Arabia

[2] Aligarh Muslim Univ, Fac Engn & Technol, Dept Appl Phys, Aligarh, Uttar Pradesh, India

[3] Tech Univ Lodz, Inst Gen & Ecol Chem, Zeromskiego 116, PL-90924 Lodz, Poland

[4] Dongguk Univ, Div Biosci, Gyeongju 780714, South Korea

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2017年 / 1130卷

关键词：

Copper(II) salen complex; Catalytic applications; DNA binding; Antimicrobial biofilm activity; Anticancer activity; HUMAN HEMOGLOBIN PROTEINS; HUMAN SERUM-ALBUMIN; SCHIFF-BASE LIGAND; COPPER(II) COMPLEXES; DNA CLEAVAGE; BINDING; RUTHENIUM(II); DERIVATIVES; ARYLATIONS; ANILINES;

D O I：

10.1016/j.molstruc.2016.10.021

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The catalytic property of a mononuclear Cu(II) salen complex in Chan-Lam coupling reaction with phenyl boronic acid at room temperature is reported. The studied complex is found to be potential catalyst in the preparation of carbon-heteroatom bonds with excellent yields. The studied Cu(II) salen complex is monoclinic with cell parameters, a = 9.6807(5) (alpha 90 degrees), (b = 17.2504(8) (beta 112.429 (2), c = 11.1403 (6) (gamma = 90 degrees), and has distorted square planar environment around Cu(II) ion. Furthermore, there is no pi center dot center dot center dot pi at interactions in the reported complex due to large distance between the centroid of aromatic rings. In addition, DNA binding study of Cu(II) salen complex by fluorescence and absorption spectroscopy is also reported. Moreover, the reported Cu(II) salen complex exhibits significant anticancer activity against MCF-7 cancer cell lines, and displays potential antimicrobial biofilm activity against P. aeruginosa, suggesting antimicrobial biofilm an important tool for suppression of resistant infections caused by P. aeruginosa. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：122 / 127

页数：6

共 47 条

[1] Hydroxylation of Phenol Catalyzed by Oxovanadium(IV) of Salen-Type Schiff Base Complexes with Hydrogen Peroxide [J].